Maicox (Fluconazole)

Fluconazole blocks the fungal enzyme 14α‑demethylase, a cytochrome P450 isoform needed to convert lanosterol into ergosterol. Without ergosterol, the fungal cell membrane becomes defective, leading to impaired growth or cell death. This mechanism targets a pathway that human cells do not rely on, providing selective antifungal activity.

The dosage of fluconazole is individualized by the prescribing healthcare professional based on the type and severity of the infection, patient age, renal and hepatic function, and other clinical factors. Patients should follow the exact regimen written on the prescription label and consult their prescriber for any clarification.

Fluconazole should be used in pregnancy only when the potential benefit justifies any potential risk to the fetus, as safety data are limited. For breastfeeding mothers, fluconazole does pass into breast milk in small amounts; clinicians usually weigh the benefits to the mother against possible exposure to the infant before recommending use.

To request Maicox, visit the product page on gnhindia.com, enter the desired quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Fluconazole belongs to the triazole class and offers oral administration, good bioavailability, and a relatively favorable safety profile compared with some older azoles. It is less potent against certain resistant fungi than newer agents like voriconazole or echinocandins, but its convenience and spectrum make it a first‑line choice for many Candida infections.

Maicox should be stored at ambient temperature, below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Maicox is taken orally, usually with a glass of water. The tablet (or capsule, if applicable) may be swallowed with or without food, unless the prescribing information advises otherwise. Patients should not split, crush, or chew the dosage form unless specifically instructed by a healthcare professional.

Serious adverse events, although uncommon, include liver toxicity (hepatitis or hepatic failure), severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, cardiac arrhythmias due to QT prolongation, and rare cases of anaphylaxis. Patients should seek immediate medical attention if they notice jaundice, rash, fever, or cardiac symptoms.

Fluconazole is contraindicated in individuals with a known hypersensitivity to fluconazole or any other azole antifungal. Patients taking medications that have a major interaction, such as certain systemic azoles, rifampin, or those with uncontrolled severe liver disease, should avoid use unless a prescriber determines it is safe.