Product image of Malina (Desogestrel) supplied by GNH India

Malina

Active Ingredient:
Desogestrel
Origin:
EU

Malina (Desogestrel)

Desogestrel, the active ingredient in Malina, is a progestin presented as a tablet for oral use. It provides hormonal contraception by preventing ovulation and creating cervical mucus changes that inhibit fertilization in women of reproductive age.

GNH India supplies Malina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Biomo Pharma Gmbh

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Indications & Clinical Uses

  • Desogestrel is a progestin‑only oral contraceptive that acts within the reproductive hormone pathway to prevent pregnancy.
  • Contraception: provides reliable birth control for women of childbearing potential.
  • Ovulation inhibition: suppresses the luteinizing hormone surge to prevent egg release.
  • Cervical mucus alteration: thickens mucus to reduce sperm penetration.

How It Works

  • Desogestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge and thereby inhibiting ovulation. It also induces changes in cervical mucus, making it less permeable to sperm, and alters the endometrial lining to reduce the likelihood of implantation.

Side Effects

Desogestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Irregular vaginal bleeding or spotting
  • Headache
  • Nausea or abdominal discomfort
  • Breast tenderness
  • Weight gain or fluid retention
  • Mood changes or irritability

Serious or Rare Side Effects

  • Deep vein thrombosis or pulmonary embolism
  • Hepatic adenoma or other liver abnormalities
  • Severe hypertension
  • Allergic reaction, including anaphylaxis
  • Visual disturbances or eye problems
  • Persistent severe abdominal pain

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Contraindicated in pregnancy: category X; avoid use during pregnancy.
  • Active thromboembolic disease: do not use in patients with current clotting disorders.
  • Smoking over age 35: increased risk of cardiovascular events; advise cessation.
  • Liver disease: monitor hepatic function and avoid in severe impairment.
  • Blood pressure monitoring: check regularly, especially in hypertensive patients.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Desogestrel can interact with several medicines, affecting its contraceptive efficacy.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin): markedly reduce plasma levels.
  • Rifampin or other strong inducers: decrease effectiveness of contraception.
  • St. John’s wort: may lower contraceptive reliability.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (e.g., ketoconazole): may increase desogestrel concentrations.
  • Protease inhibitor antiretrovirals: potential alteration of metabolism.
  • Certain antibiotics (e.g., tetracycline): possible reduced contraceptive effect, though clinical significance is uncertain.

Frequently Asked Questions

Malina is a progestin‑only oral contraceptive that provides reliable birth control for women of reproductive age. It works by preventing ovulation, thickening cervical mucus, and altering the endometrium to reduce the chance of fertilization and implantation.

Desogestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge and thereby inhibiting ovulation. It also creates a cervical mucus environment that is hostile to sperm and modifies the uterine lining to make implantation unlikely.

The prescribed dose of Malina is determined by a qualified healthcare professional. Typically, the regimen involves taking one tablet daily at the same time each day, but the exact schedule should follow the prescriber’s instructions.

Malina is contraindicated in pregnancy (Category X) and should not be started in pregnant women. While limited data exist for breastfeeding, the product is generally not recommended unless the benefits outweigh potential risks, and a clinician should evaluate each case.

To order Malina, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike combined oral contraceptives that contain estrogen and progestin, Malina contains only desogestrel, eliminating estrogen‑related risks such as thromboembolism in certain populations. It is suitable for women who cannot tolerate estrogen, but may have a slightly higher rate of breakthrough bleeding compared with combined pills.

Malina tablets should be stored at ambient temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.

Malina is taken orally as a tablet. Swallow the tablet whole with water, preferably at the same time each day. No food restrictions are required, but consistent daily intake helps maintain contraceptive effectiveness.

The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), severe hypertension, and rare hepatic tumors. Patients should seek immediate medical attention if they experience unexplained leg pain, shortness of breath, severe headache, or visual changes.

Malina should not be used by women who are pregnant, have active thromboembolic disease, severe liver impairment, known hypersensitivity to desogestrel, or who smoke cigarettes and are over 35 years old. Consultation with a healthcare provider is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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