Product image of Maltofer (Iron (Iii) Ion) supplied by GNH India

Maltofer

Active Ingredient:
Iron (Iii) Ion
Origin:
EU

Maltofer (Iron (Iii) Ion)

Iron (III), the active ingredient in Maltofer, is an iron supplement presented as an oral tablet for oral use. It treats iron deficiency anemia and helps prevent iron deficiency in individuals at risk.

GNH India supplies Maltofer as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vifor France

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Indications & Clinical Uses

Maltofer is an iron supplement used to address disorders of iron metabolism and related anemia.

  • Iron deficiency anemia: improves hemoglobin concentration and red cell production.
  • Iron deficiency (preventive): restores depleted iron stores in at‑risk patients.
  • Chronic kidney disease‑associated anemia: supports erythropoiesis when oral iron is indicated.
  • Pregnancy‑related iron deficiency: maintains maternal iron status and fetal development.
  • Pediatric iron deficiency: promotes normal growth and development in children.

How It Works

  • Maltofer provides bioavailable ferric iron that is reduced to ferrous iron in the gastrointestinal tract and absorbed via divalent metal transporter‑1. The absorbed iron enters the plasma, binds to transferrin, and is delivered to the bone marrow for incorporation into hemoglobin and other iron‑dependent enzymes, thereby supporting erythropoiesis and cellular metabolism.

Side Effects

Maltofer may cause a range of adverse reactions, most of which are related to gastrointestinal irritation or iron overload.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Abdominal discomfort: cramping or pain in the abdomen.
  • Constipation: reduced bowel movements.
  • Diarrhea: loose stools.
  • Dark stools: discoloration due to unabsorbed iron.
  • Metallic taste: transient metallic sensation in the mouth.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Severe hypotension: sudden drop in blood pressure.
  • Iron overload: accumulation of iron in organs leading to toxicity.
  • Hepatic injury: liver function abnormalities.
  • Hemolysis: destruction of red blood cells.
  • Severe gastrointestinal bleeding: significant blood loss from the GI tract.

Precautions & Warnings

When prescribing Maltofer, clinicians should consider several safety measures.

  • Assess iron status before initiating: confirm deficiency with laboratory tests.
  • Monitor hemoglobin and ferritin: adjust therapy based on response.
  • Avoid in known hypersensitivity: discontinue if allergic signs appear.
  • Caution in inflammatory bowel disease: iron may exacerbate intestinal irritation.
  • Use with caution in chronic liver disease: risk of iron accumulation.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Maltofer can interact with other medicines that affect iron absorption or increase gastrointestinal risk.

Major Interactions (Avoid)

  • Tetracycline antibiotics: chelation reduces absorption of both agents.
  • Levothyroxine: iron decreases levothyroxine bioavailability.
  • Antacids containing aluminum or magnesium: impair iron uptake.
  • Phosphate binders: compete for absorption sites.
  • Fluoroquinolone antibiotics: form insoluble complexes reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Proton pump inhibitors: may lower iron absorption.
  • Calcium supplements: compete for intestinal transport.
  • Vitamin C: can increase iron absorption, potentially leading to excess.
  • NSAIDs: combined use may heighten gastrointestinal irritation.
  • Oral contraceptives: possible reduction in contraceptive effectiveness.

Frequently Asked Questions

Maltofer is an oral iron (III) supplement indicated for the treatment of iron deficiency anemia and for the prevention of iron deficiency in individuals at risk, such as pregnant women, children, and patients with chronic diseases that affect iron status.

Iron (III) from Maltofer is reduced to ferrous iron in the gut, absorbed via specific transporters, and then bound to transferrin in the bloodstream. It is delivered to the bone marrow where it is incorporated into hemoglobin, supporting red blood cell production and overall cellular metabolism.

The dosage of Maltofer is individualized. A qualified prescriber determines the appropriate amount based on the patient’s iron levels, age, weight, and clinical condition, and provides specific instructions for use.

Safety data for Maltofer in pregnancy and lactation are limited. It should only be used if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant. Consultation with a healthcare professional is essential.

To order Maltofer, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Maltofer provides ferric iron in a formulation designed for oral administration, offering comparable efficacy to other oral iron salts such as ferrous sulfate. Differences may include tolerability, elemental iron content, and specific absorption characteristics, which should be discussed with a prescriber.

Maltofer should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the container tightly closed and out of reach of children.

Maltofer is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with a small amount of food may reduce gastrointestinal discomfort. Follow the prescriber’s instructions regarding timing and any dietary considerations.

Serious risks include severe allergic reactions such as anaphylaxis, iron overload leading to organ toxicity, and rare cases of severe gastrointestinal bleeding. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, swelling, or persistent vomiting.

Maltofer should be avoided in individuals with known hypersensitivity to iron preparations, those with iron overload disorders such as hemochromatosis, and patients with active gastrointestinal bleeding until the cause is treated. A healthcare professional should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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