Maltofer (Iron (Iii) Ion)

Maltofer is an iron supplement used to correct iron deficiency across several clinical situations.

• Iron deficiency anemia: restores hemoglobin levels and alleviates fatigue.
• Prevention of iron deficiency in pregnancy: supports maternal iron stores for fetal development.
• Iron deficiency due to chronic blood loss: replenishes iron lost from gastrointestinal bleeding or menstrual disorders.

• Iron polymaltose complex delivers elemental iron that is absorbed in the duodenum and proximal jejunum. The released iron is incorporated into hemoglobin and myoglobin, facilitating oxygen transport and supporting erythropoiesis. By providing bioavailable iron, the complex corrects depleted iron stores and normalizes iron‑dependent enzymatic processes.

Common adverse reactions are usually mild and related to gastrointestinal tolerance.

Common Side Effects

• Nausea: mild to moderate upset stomach.
• Constipation: reduced bowel movements.
• Diarrhoea: loose stools in some patients.
• Abdominal discomfort: cramping or pain.
• Dark coloured stools: harmless change in stool colour.
• Metallic taste: transient alteration in taste perception.

Serious or Rare Side Effects

• Severe allergic reaction: rash, itching, swelling, or anaphylaxis.
• Iron overload: excessive iron accumulation leading to organ damage.
• Hepatic injury: abnormal liver function tests.
• Severe abdominal pain: persistent or worsening pain.
• Hypotension: sudden drop in blood pressure.
• Hemolysis: rapid destruction of red blood cells.

Before initiating therapy, assess iron status and monitor response during treatment.

• Baseline assessment: confirm iron deficiency with laboratory tests.
• Monitoring: check hemoglobin and ferritin periodically.
• Hypersensitivity: discontinue if signs of allergic reaction appear.
• Gastrointestinal disease: use with caution in patients with IBD or ulcer disease.
• Concomitant iron products: avoid using multiple iron supplements simultaneously.
• Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Iron absorption can be affected by several co‑administered medicines.

Major Interactions (Avoid)

• Tetracycline antibiotics: chelation reduces efficacy of both agents.
• Fluoroquinolone antibiotics: chelation impairs absorption.
• Levothyroxine: iron may decrease thyroid hormone absorption.
• Bisphosphonates: concurrent intake lowers absorption of both drugs.
• Antacids containing aluminium or magnesium: markedly reduce iron uptake.

Moderate Interactions (Monitor Closely)

• Proton pump inhibitors: may modestly decrease iron absorption.
• H2‑blockers: can reduce gastric acidity affecting iron uptake.
• Calcium supplements or dairy products: compete for absorption pathways.
• Foods high in phytates (e.g., legumes, whole grains): may lower iron bioavailability.
• Vitamin C rich foods or supplements: can increase iron absorption, requiring dose adjustment.