Manidipina Teva (Manidipine Dihydrochloride)

Manidipine blocks L‑type calcium channels in vascular smooth‑muscle cells, reducing calcium entry. This causes vasodilation, decreasing peripheral vascular resistance and ultimately lowering systolic and diastolic blood pressure.

The dosage of manidipine is individualized by the prescribing clinician based on the patient’s blood‑pressure profile, age, renal and hepatic function, and concomitant therapies. Patients should follow the prescriber’s instructions.

Safety of manidipine in pregnancy and lactation has not been established. It should be avoided unless the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Manidipine belongs to the dihydropyridine calcium‑channel blocker class, offering potent vasodilation with a relatively low incidence of reflex tachycardia compared with some older agents. Unlike ACE inhibitors or ARBs, it does not affect the renin‑angiotensin system, making it a useful alternative or add‑on therapy.

Manidipina Teva tablets should be stored below 25 °C, in the original packaging, protected from moisture and direct sunlight. Do not store in bathrooms or near heat sources.

Manidipina Teva is taken orally, usually once daily with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically advised.

Serious adverse events, though rare, include severe hypotension, myocardial infarction, hepatic dysfunction, allergic reactions such as rash or angioedema, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience any of these symptoms.

Manidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation, and should be used with caution in individuals with severe hepatic impairment, uncontrolled heart failure, or those who are pregnant or breastfeeding without clear medical justification.