Mann (Paracetamol, Caffeine)

Paracetamol works by centrally inhibiting cyclooxygenase enzymes, which reduces prostaglandin production and therefore lowers pain perception and body temperature. Caffeine blocks adenosine receptors in the brain, producing a stimulant effect and increasing alertness. This antagonism also amplifies the pain‑relieving action of paracetamol, resulting in a more pronounced analgesic response.

The appropriate dose of Mann is determined by a qualified healthcare professional based on the individual’s age, weight, clinical condition and any other medications being taken. Prescribers follow local guidelines for paracetamol‑caffeine combinations and adjust the regimen to achieve effective symptom control while minimizing risk.

Safety data for the combined use of paracetamol and caffeine during pregnancy or lactation are limited. Paracetamol alone is generally considered low‑risk when used at recommended doses, but caffeine crosses the placenta and is excreted in breast milk. Women who are pregnant or breastfeeding should consult their healthcare provider before using Mann.

To place an order, submit an enquiry on the Mann product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Mann combines paracetamol with caffeine, offering a synergistic effect that can be more effective for certain headaches and mild pain than paracetamol alone. Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen, Mann does not carry the same gastrointestinal or cardiovascular risks, but it also lacks anti‑inflammatory activity. Choice of therapy depends on the patient’s medical history and specific symptom profile.

Mann tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments. Do not use the tablets after the expiry date printed on the pack.

Mann is taken orally with a glass of water. The tablet should be swallowed whole; it is not intended to be chewed, crushed or dissolved. Patients should follow the dosing instructions provided by their prescriber or the product label, and should not exceed the maximum daily amount of paracetamol contained in the combination.

The most serious risks include severe allergic reactions such as rash, swelling or anaphylaxis, and rare cases of liver toxicity, especially when the recommended maximum daily dose of paracetamol is exceeded. Patients should seek immediate medical attention if they notice signs of a serious skin reaction, persistent nausea, jaundice, or any symptoms suggestive of an allergic response.

Mann should be avoided by individuals with known hypersensitivity to paracetamol, caffeine or any excipients in the tablet. It is also contraindicated in patients with severe hepatic impairment, uncontrolled hypertension, or those taking monoamine oxid