Product image of Manorin (Gadoteric Acid) supplied by GNH India

Manorin

Active Ingredient:
Gadoteric Acid
Origin:
EU

Manorin (Gadoteric Acid)

Gadoteric Acid, the active ingredient in Manorin, is a gadolinium-based contrast agent presented as an injectable solution for intravenous use. It enhances magnetic resonance imaging by increasing signal intensity, aiding the detection of lesions and vascular structures in patients undergoing diagnostic scans.

GNH India supplies Manorin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company ensures quality compliance with EU regulations and provides reliable distribution to healthcare facilities across multiple regions.

Manufacturer / TM Owner

Demo Abee

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Manorin (gadoteric acid) is used as a contrast agent in magnetic resonance imaging (MRI) procedures.
  • Brain MRI: improves detection and delineation of intracranial lesions and tumors.
  • Spine MRI: enhances visualization of spinal cord, intervertebral discs, and surrounding tissues.
  • Abdominal and pelvic MRI: increases contrast between vascular structures and organs, facilitating assessment of lesions.

How It Works

  • Gadoteric Acid is a paramagnetic gadolinium chelate that shortens the T1 relaxation time of nearby water protons. After intravenous injection it distributes into the extracellular space, transiently altering magnetic properties and producing a higher signal on T1‑weighted MRI sequences. This increased signal intensity highlights vascularized tissues and lesions, allowing radiologists to obtain clearer anatomical detail.

Side Effects

Adverse reactions to Manorin may vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate feeling of sickness.
  • Headache: transient discomfort.
  • Warm sensation: feeling of heat at the injection site.
  • Dizziness: light‑headedness shortly after administration.
  • Metallic taste: brief taste alteration.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring emergency treatment.
  • Nephrogenic systemic fibrosis (NSF): rare fibrotic condition in patients with severe renal impairment.
  • Severe hypotension: marked drop in blood pressure potentially leading to shock.

Precautions & Warnings

  • When using Manorin, clinicians should observe several safety precautions to minimize risk.
  • Renal function assessment: evaluate glomerular filtration rate before administration.
  • Use in patients with adequate renal function: avoid in severe renal impairment.
  • Hypersensitivity screening: discontinue if prior allergic reaction to gadolinium agents.
  • Monitor for immediate reactions: observe patient for at least 30 minutes post‑injection.
  • Dose minimization: employ the lowest effective dose for diagnostic purpose.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Manorin may interact with other medicines or agents, requiring attention to potential effects.

Major Interactions (Avoid)

  • Renal toxic drugs (e.g., high‑dose aminoglycosides): increase risk of NSF.
  • Concurrent gadolinium‑based agents: cumulative gadolinium load may heighten toxicity.
  • Iron chelators (e.g., deferoxamine): may destabilize gadolinium chelate.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect renal clearance of gadolinium.
  • Iodinated contrast agents: combined use can stress kidney function.
  • Beta‑blockers: may mask early signs of anaphylaxis.

Frequently Asked Questions

Manorin contains gadoteric acid, a gadolinium‑based contrast agent administered intravenously to enhance magnetic resonance imaging. It improves the visibility of blood vessels, lesions, and tissue structures, supporting accurate diagnosis in brain, spine, abdominal and pelvic MRI examinations.

Gadoteric acid is a paramagnetic chelate that shortens the T1 relaxation time of nearby water protons. When injected, it temporarily alters magnetic properties of tissues, producing a brighter signal on T1‑weighted MRI scans and thereby highlighting vascularized or pathological areas.

The dose of Manorin is determined by the prescribing physician based on the specific MRI study, patient weight, and renal function. Dosing guidelines are provided in the product labeling and should be individualized for each patient.

Safety of gadoteric acid during pregnancy or lactation has not been fully established. It should only be used when the potential diagnostic benefit outweighs any possible risk to the fetus or infant, and the decision must be made by the treating clinician.

To order Manorin, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Manorin (gadoteric acid) belongs to the macrocyclic gadolinium‑based contrast agents, which generally exhibit higher kinetic stability than linear agents. This stability reduces the risk of gadolinium release, offering a favorable safety profile, especially in patients with moderate renal function, while providing comparable image enhancement.

Manorin should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Keep the product in its original packaging until use to maintain stability and potency.

Manorin is administered as an intravenous injection, typically as a rapid bolus immediately before the MRI scan. The injection is performed by qualified healthcare personnel using aseptic technique, and patients are observed for any immediate reactions.

The most serious risks include severe allergic reactions such as anaphylaxis, nephrogenic systemic fibrosis (NSF) in patients with severe renal impairment, and profound hypotension. Prompt recognition and management of these events are essential.

Manorin should be avoided in patients with known hypersensitivity to gadolinium‑based agents, those with severe renal impairment (eGFR <30 mL/min/1.73 m²), or in individuals with a history of NSF. Clinicians must assess renal function and allergy history before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Gadoteric Acid

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT