Mantomed (Memantine Hydrochloride)

Memantine acts as a non‑competitive antagonist at NMDA receptors. By blocking excessive calcium influx caused by prolonged glutamate stimulation, it limits excitotoxic injury while allowing normal synaptic activity, which can slow the progression of neurodegeneration in Alzheimer’s disease.

The dosage of Mantomed is individualized by the prescribing clinician based on the patient’s clinical condition, renal function, and tolerability. The prescriber determines the appropriate strength, titration schedule, and maintenance dose.

Safety data for memantine in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To request Mantomed, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mantomed (memantine) belongs to the NMDA‑receptor antagonist class, which differs from cholinesterase inhibitors such as donepezil. While cholinesterase inhibitors enhance acetylcholine signaling, memantine reduces glutamate‑mediated excitotoxicity. The choice of therapy depends on disease stage, patient tolerance and clinician judgment.

Mantomed should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from excess moisture, heat and direct sunlight to maintain its stability and potency.

Mantomed is taken orally, usually once daily with or without food, as directed by the prescribing physician. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include seizures, severe allergic reactions (anaphylaxis), hallucinations or psychosis, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience any of these symptoms while on therapy.

Mantomed is contraindicated in patients with known hypersensitivity to memantine or any excipients, and it should be used with caution in individuals with severe renal impairment, uncontrolled seizures, or those taking other NMDA‑receptor antagonists.