Product image of Marbodin (Memantine) supplied by GNH India

Marbodin

Active Ingredient:
Memantine
Origin:
EU

Marbodin (Memantine)

Memantine, the active ingredient in Marbodin, is a NMDA receptor antagonist presented as a tablet for oral use. It is indicated for the treatment of moderate to severe Alzheimer's disease in adult patients.
GNH India supplies Marbodin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Memantine is used in the management of neurodegenerative conditions affecting cognition, particularly within the Alzheimer’s disease spectrum.
  • Alzheimer's disease (moderate): Improves cognitive function and daily living activities in patients with moderate disease severity.
  • Alzheimer's disease (severe): Helps maintain functional abilities and may slow further decline in severe cases.
  • Behavioral symptoms in Alzheimer's disease: May reduce agitation and improve overall patient behavior.

How It Works

  • Memantine acts as a non‑competitive antagonist at the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor-associated ion channel, it blocks excessive calcium influx caused by prolonged glutamate activation, thereby reducing excitotoxic neuronal injury and supporting neuronal survival in the brain.

Side Effects

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion
  • Hypertension
  • Insomnia

Serious or Rare Side Effects

  • Seizures
  • Severe allergic reactions (rash, swelling, anaphylaxis)
  • Cardiac arrhythmias
  • Hepatic dysfunction (elevated liver enzymes)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or behavior

Precautions & Warnings

  • Memantine should be used with caution in patients with certain medical conditions and in specific situations.
  • Renal impairment: Adjust dose and monitor renal function.
  • Hepatic impairment: Use with caution and monitor liver enzymes.
  • History of seizures: May increase seizure risk; monitor closely.
  • Concurrent use with other NMDA antagonists: Avoid additive neuro‑psychiatric effects.
  • Pregnancy: Safety not established; weigh benefits against potential risks.
  • Store at ambient temperature: Keep in original packaging, protect from moisture and direct light.

Avoid Interactions

Memantine may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Amantadine: Increased risk of neuropsychiatric side effects.
  • Ketamine: Additive NMDA antagonism may cause excessive CNS depression.
  • Other NMDA antagonists: Potential for severe neurotoxicity.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: May diminish cognitive benefits.
  • CNS depressants (e.g., benzodiazepines): May enhance dizziness and sedation.
  • Diuretics: May alter plasma concentrations of memantine.
  • Proton pump inhibitors: May affect drug absorption.
  • Antihypertensives: Possible additive effect on blood pressure.

Frequently Asked Questions

Marbodin contains memantine, which is prescribed to treat moderate to severe Alzheimer's disease. It helps improve cognition, functional abilities, and may reduce behavioral symptoms in patients with this form of dementia.

Memantine blocks the NMDA receptor channel in a non‑competitive manner, preventing excessive calcium entry caused by overstimulation with glutamate. This reduces excitotoxic neuronal damage, supporting neuronal health and function in the central nervous system.

The specific dose of Marbodin is determined by the prescribing clinician based on the patient’s condition, age, renal function, and other factors. The prescriber will set the appropriate dosage and titration schedule.

Safety of memantine in pregnancy and lactation has not been fully established. Healthcare providers should evaluate the potential benefits against possible risks before prescribing Marbodin to pregnant or nursing women.

To request Marbodin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Marbodin (memantine) belongs to the NMDA‑receptor antagonist class, differing from acetylcholinesterase inhibitors such as donepezil. While both improve cognition, memantine is typically used for moderate to severe disease and has a distinct side‑effect profile, making it a complementary option in many treatment regimens.

Marbodin should be stored at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, heat and direct sunlight to maintain product stability.

Marbodin is taken orally, usually as a tablet, with or without food as directed by the prescriber. The exact administration schedule is individualized for each patient.

Serious risks include seizures, severe allergic reactions, cardiac arrhythmias, hepatic dysfunction, and rare skin reactions such as Stevens‑Johnson syndrome. Patients should be monitored for these events, especially during treatment initiation.

Marbodin is contraindicated in patients with known hypersensitivity to memantine or any component of the formulation. Caution is also advised for individuals with uncontrolled severe renal or hepatic impairment, or those taking other NMDA antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Memantine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT