Product image of Marbodin (Memantine) supplied by GNH India

Marbodin

Active Ingredient:
Memantine
Origin:
EU

Marbodin (Memantine)

Memantine, the active ingredient in Marbodin, is a NMDA receptor antagonist presented as an oral tablet for oral use. It is used to treat Alzheimer’s disease in adult patients.
GNH India supplies Marbodin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Memantine acts on the glutamatergic pathway and is indicated for Alzheimer’s disease.

  • Alzheimer’s disease: helps improve cognition and functional abilities in moderate to severe stages.

How It Works

  • Memantine is a non‑competitive antagonist of the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor channel at a site distinct from the glutamate binding site, it reduces excessive calcium influx caused by prolonged glutamate activation, thereby limiting excitotoxic neuronal injury that contributes to cognitive decline in Alzheimer’s disease.

Side Effects

Common side effects are generally mild and may resolve with continued therapy.

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion

Serious or Rare Side Effects

  • Seizures
  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Hallucinations or psychosis
  • Cardiac arrhythmias

Precautions & Warnings

Memantine requires careful consideration in several clinical situations.

  • Renal impairment: dose adjustment may be necessary.
  • Hepatic impairment: monitor liver function.
  • History of seizures: observe for increased seizure activity.
  • Concomitant NMDA antagonists: avoid combined use.
  • Pregnancy: safety not established; use only if clearly needed.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Memantine can interact with several drug classes; monitoring is advised.

Major Interactions (Avoid)

  • Other NMDA antagonists (e.g., amantadine): additive neuro‑blocking effects.
  • Strong CYP450 inhibitors (e.g., ketoconazole): may increase memantine levels.
  • Strong CYP450 inducers (e.g., rifampin): may reduce therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may worsen cognitive symptoms.
  • CNS depressants (e.g., benzodiazepines): increased sedation risk.
  • Diuretics: monitor electrolyte balance and renal function.

Frequently Asked Questions

Marbodin contains memantine, which is prescribed to treat moderate to severe Alzheimer’s disease. It works by protecting brain cells from excess glutamate activity, helping to maintain cognition and daily functioning in affected patients.

Memantine blocks the NMDA receptor’s ion channel in a non‑competitive manner, reducing calcium influx caused by overstimulation with glutamate. This limits excitotoxic damage to neurons, a key factor in the progression of Alzheimer’s disease.

The specific dose of Marbodin is determined by the prescribing clinician based on the patient’s condition, age, renal function and other factors. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety of memantine in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Marbodin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Memantine belongs to the NMDA‑receptor antagonist class, differing from acetylcholinesterase inhibitors such as donepezil. While both improve symptoms, memantine is typically used in moderate to severe stages and may be combined with an acetylcholinesterase inhibitor for additive benefit.

Marbodin should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability.

Marbodin is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless instructed otherwise.

Serious risks include the potential for seizures, severe allergic reactions, hallucinations, and cardiac arrhythmias. Patients should be monitored for these events, and any sudden changes in neurological or cardiac status should prompt immediate medical evaluation.

Marbodin is contraindicated in patients with known hypersensitivity to memantine or any of its excipients. Caution is also advised for individuals with severe renal impairment, uncontrolled seizures, or those taking other NMDA antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.