Product image of Maresyl (Xylometazoline Hydrochloride) supplied by GNH India

Maresyl

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Maresyl (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Maresyl, is an imidazoline nasal decongestant presented as a nasal spray for topical nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children when appropriate, and can be used safely under medical guidance.

GNH India supplies Maresyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to global quality standards and provides reliable sourcing for regulated global markets.

Manufacturer / TM Owner

Jadran - Galenski Laboratorij, D.O.O. Ljubljana

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Xylometazoline Hydrochloride is used as a topical nasal decongestant to alleviate swelling of the nasal mucosa in several upper‑respiratory conditions.

  • Common cold nasal congestion: reduces swelling of nasal passages, improving airflow.
  • Acute sinusitis: alleviates blockage of sinus ostia, facilitating drainage.
  • Allergic rhinitis: diminishes nasal edema caused by allergen exposure, relieving symptoms.

How It Works

  • Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic agonist on the α1‑ and α2‑receptors of the nasal mucosal blood vessels. Stimulation of these receptors induces vasoconstriction, which decreases blood flow and reduces edema of the nasal mucosa, leading to rapid relief of congestion. The effect is localized, with minimal systemic absorption, and the onset of action occurs within minutes, lasting for several hours.

Side Effects

Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal burning or stinging sensation
  • Nasal dryness or crusting
  • Sneezing
  • Headache
  • Altered taste
  • Mild epistaxis

Serious or Rare Side Effects

  • Severe nasal bleeding
  • Allergic reaction including rash, itching or swelling
  • Hypertension or elevated blood pressure
  • Tachycardia
  • Rebound congestion (rhinitis medicamentosa) with prolonged use
  • Nasal septum perforation

Precautions & Warnings

When using Xylometazoline Hydrochloride, consider the following precautions to ensure safe and effective therapy.

  • Duration of use: limit treatment to 3‑5 days to avoid rebound congestion.
  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: caution, as limited data are available.
  • Cardiovascular disease: use with caution in patients with hypertension or heart disease.
  • Nasal conditions: avoid in individuals with severe nasal septum perforation or recent nasal surgery.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline Hydrochloride can interact with other medications; awareness of major and moderate interactions helps prevent adverse effects.

Major Interactions (Avoid)

  • Sympathomimetic agents (e.g., phenylephrine, pseudoephedrine): additive vasoconstriction may raise blood pressure.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis when combined with nasal decongestants.

Moderate Interactions (Monitor Closely)

  • Antihypertensive drugs: nasal decongestant may diminish their blood‑pressure‑lowering effect.
  • Tricyclic antidepressants: possible increase in blood pressure.
  • Other nasal decongestants: concurrent use raises risk of over‑dosage and rebound congestion.

Frequently Asked Questions

Maresyl contains Xylometazoline Hydrochloride, an OTC nasal decongestant indicated for temporary relief of nasal congestion caused by the common cold, acute sinusitis, and allergic rhinitis. It works by shrinking swollen blood vessels in the nasal passages, helping restore normal airflow.

Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. By activating α1‑ and α2‑receptors on nasal mucosal vessels, it causes vasoconstriction, which reduces blood flow and edema in the nasal lining. The resulting decrease in swelling quickly eases congestion.

The appropriate dose of Maresyl is determined by a qualified healthcare professional based on the patient’s age, condition and response. Typically, adults may be instructed to spray one or two sprays per nostril every 8‑10 hours, not exceeding the maximum daily frequency advised by the prescriber.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a healthcare provider.

To request Maresyl, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Maresyl’s active ingredient, Xylometazoline, belongs to the imidazoline class, which typically provides rapid onset of action and a duration of several hours. Compared with phenylephrine‑based sprays, Xylometazoline often has a slightly longer effect and may be better tolerated, though individual response can vary.

Store Maresyl at room temperature, below 25 °C, in its original packaging. Protect the container from moisture, direct sunlight and extreme temperatures. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Maresyl is applied as a nasal spray. The user gently inserts the tip into each nostril, presses the pump to deliver the prescribed number of sprays, and then inhales lightly. The recommended frequency and maximum daily dose should follow the instructions given by the prescribing clinician.

Serious adverse events, though rare, include severe nasal bleeding, allergic reactions such as rash or swelling, marked hypertension, tachycardia, and rebound congestion (rhinitis medicamentosa) after prolonged use. If any of these occur, discontinue the product and seek medical attention promptly.

Maresyl should be avoided in individuals with known hypersensitivity to Xylometazoline or any excipients, in patients with severe nasal septum perforation or recent nasal surgery, and in those for whom prolonged use (beyond 3‑5 days) is contraindicated. Children under the age recommended on the label should also not use it without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.