Marevan (Warfarin Sodium)

Warfarin sodium blocks the vitamin K epoxide reductase enzyme, which is needed to recycle vitamin K. This inhibition lowers the production of clotting factors II, VII, IX, and X, decreasing the blood’s ability to form clots.

The dose of Marevan is individualized. A qualified prescriber determines the appropriate amount based on the patient’s INR target, clinical condition, and response to therapy.

Warfarin can cross the placenta and is generally contraindicated in pregnancy because of fetal bleeding risk. Its safety during breastfeeding is also limited; clinicians should evaluate risks and consider alternative therapies.

To order Marevan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Marevan (warfarin) is a vitamin K antagonist, whereas newer oral anticoagulants (e.g., direct thrombin or factor Xa inhibitors) act on specific clotting enzymes and often require less routine monitoring. Warfarin offers a long clinical history and a reversible effect with vitamin K, but it demands regular INR checks.

Marevan should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and heat sources to maintain stability.

Marevan is taken orally, usually once daily, with or without food. The exact timing and dosage are set by the prescribing clinician and may be adjusted based on INR monitoring.

The most critical risks include severe or uncontrolled bleeding, hemorrhagic stroke, and rare skin necrosis. Patients should be educated to recognize signs such as unusual bruising, blood in urine or stool, and sudden severe headache.

Marevan is contraindicated in patients with active major bleeding, recent intracranial hemorrhage, severe uncontrolled hypertension, or known hypersensitivity to warfarin. It should also be used with caution in individuals with liver disease, pregnancy, or a history of bleeding disorders.