Mastical D (Colecalciferol, Calcium)

Colecalciferol is converted first to 25‑hydroxyvitamin D in the liver and then to the active hormone 1,25‑dihydroxyvitamin D in the kidney. This active form binds to vitamin D receptors, enhancing the expression of calcium‑binding proteins in the intestine, which increases calcium absorption and promotes bone mineralization.

The appropriate dose of Mastical D is determined by a prescriber based on the patient’s age, clinical condition, baseline vitamin D and calcium levels, and any concurrent therapies. Patients should follow the specific dosing instructions provided by their healthcare professional.

Pregnant or breastfeeding individuals should only use Mastical D after consulting a healthcare professional. Vitamin D and calcium are essential nutrients during these periods, but dosing must be individualized to avoid excess intake that could affect maternal or fetal health.

To place an order, submit an enquiry on the Mastical D product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Mastical D combines both colecalciferol (vitamin D3) and elemental calcium in a single oral tablet, whereas many vitamin D products contain only the vitamin. This dual formulation can simplify therapy for patients who need both nutrients, but clinicians may choose separate products based on individual dosing requirements or specific patient conditions.

Mastical D should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.

Mastical D is taken orally, usually with water. The tablet should be swallowed whole and not chewed or crushed unless a healthcare professional advises otherwise. It can be taken with or without food, but consistent administration with meals may improve calcium absorption.

The most serious risks include severe hypercalcemia, which can lead to kidney stones, cardiac arrhythmias, or soft‑tissue calcification, and hypervitaminosis D, which may cause nausea, vomiting, weakness, and in extreme cases, renal failure. Patients should be monitored for symptoms and have serum calcium checked regularly.

Mastical D should be avoided in individuals with known hypersensitivity to colecalciferol, calcium, or any excipients, as well as patients with untreated hypercalcemia, severe renal impairment, or conditions such as sarcoidosis where vitamin D metabolism is altered, unless a physician determines it is appropriate.