Product image of Mastical D Unidia (Colecalciferol, Calcium) supplied by GNH India

Mastical D Unidia

Active Ingredient:
Colecalciferol, Calcium
Origin:
EU

Mastical D Unidia (Colecalciferol, Calcium)

Colecalciferol, the active ingredient in Mastical D Unidia, is a nutrition supplement presented as an oral formulation for oral use. It supports calcium metabolism and bone health, particularly in individuals with vitamin D or calcium deficiency.
GNH India supplies Mastical D Unidia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Mastical D Unidia provides vitamin D3 and calcium to address conditions related to bone and mineral metabolism.

  • Calcium and vitamin D deficiency: helps restore normal serum levels.
  • Osteoporosis prevention: supports maintenance of bone mineral density.
  • Hypocalcemia: assists in raising low calcium concentrations in the blood.
  • Post‑menopausal bone loss: contributes to reduced bone turnover.
  • Pediatric rickets risk: supplies essential nutrients for proper bone development.

How It Works

  • Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidneys to the active hormone calcitriol, which binds to vitamin D receptors in intestinal cells to increase calcium and phosphate absorption. The added calcium provides the mineral substrate required for bone mineralization, together promoting skeletal strength and normal calcium homeostasis.

Side Effects

Mastical D Unidia may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Hypercalcemia symptoms such as mild nausea.
  • Gastrointestinal discomfort, including constipation.
  • Headache or dizziness.
  • Dry mouth or metallic taste.
  • Mild fatigue.

Serious or Rare Side Effects

  • Severe hypercalcemia leading to cardiac arrhythmia.
  • Kidney stone formation.
  • Allergic reactions such as rash or angioedema.
  • Hypervitaminosis D with prolonged excess intake.
  • Acute pancreatitis (very rare).

Precautions & Warnings

Before using Mastical D Unidia, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Renal impairment: monitor serum calcium and vitamin D levels.
  • Existing hypercalcemia: avoid supplementation.
  • Concomitant thiazide diuretics: increased risk of elevated calcium.
  • Pediatric use: dosage may differ; follow prescriber guidance.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Mastical D Unidia can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Thiazide diuretics: may cause dangerous hypercalcemia.
  • Lithium: can alter calcium metabolism.
  • High-dose vitamin A supplements: increase risk of hypervitaminosis D.

Moderate Interactions (Monitor Closely)

  • Bisphosphonates: may affect calcium balance.
  • Corticosteroids: can reduce calcium absorption.
  • Anticonvulsants such as phenytoin: may increase vitamin D metabolism.

Frequently Asked Questions

Mastical D Unidia is a nutrition supplement that provides vitamin D3 (colecalciferol) and calcium. It is used to support normal calcium metabolism, maintain bone health, and address deficiencies of vitamin D or calcium in adults and children under medical supervision.

Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidneys to the active hormone calcitriol. Calcitriol binds to vitamin D receptors in the intestine, increasing absorption of calcium and phosphate, which are essential for bone mineralization and overall calcium balance.

The appropriate dose of Mastical D Unidia is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, laboratory values, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Pregnant or breastfeeding individuals should discuss use of Mastical D Unidia with their healthcare provider. Vitamin D and calcium are important nutrients, but dosing must be individualized to avoid excess, which could affect maternal and fetal health.

To order Mastical D Unidia, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mastical D Unidia combines colecalciferol and calcium in a single oral formulation, offering a convenient way to address both nutrients together. Compared with separate supplements, it may improve adherence, but the exact composition and dosage should be matched to patient needs, which may differ from other brands or fixed‑dose combinations.

Mastical D Unidia should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, heat, and direct sunlight to maintain potency throughout its shelf life.

Mastical D Unidia is taken orally, usually with water. The exact timing (e.g., with meals or on an empty stomach) should follow the prescriber’s guidance, as food can affect absorption of vitamin D and calcium.

The most serious risks involve excessive calcium levels, known as hypercalcemia, which can lead to kidney stones, cardiac arrhythmias, or calcification of soft tissues. Rarely, severe vitamin D toxicity (hypervitaminosis D) may occur, especially with high doses or prolonged use.

Individuals with known hypersensitivity to colecalciferol, calcium, or any excipients should avoid the product. Those with untreated hypercalcemia, severe renal disease, or certain metabolic disorders should not use it without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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