Product image of Max Strength Cold & Flu Day & Night (Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Max Strength Cold & Flu Day & Night

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Max Strength Cold & Flu Day & Night (Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, Paracetamol and Caffeine, the active ingredients in Max Strength Cold & Flu Day & Night, are a combination analgesic/antipyretic/decongestant presented as a tablet for oral use. The decongestant reduces swelling of nasal passages, the analgesic/antipyretic lowers temperature and eases aches, and caffeine adds mild stimulation to counteract drowsiness, providing day‑and‑night relief of common cold and flu symptoms in adults.

GNH India supplies Max Strength Cold & Flu Day & Night as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Max Strength Cold & Flu Day & Night, a combination analgesic/antipyretic/decongestant, is indicated for symptomatic relief of common cold and influenza.

  • Nasal congestion: reduces swelling of nasal mucosa and improves airflow.
  • Fever: lowers elevated body temperature.
  • Pain and aches: alleviates headache, sore throat, and muscle discomfort.

How It Works

  • Phenylephrine acts as a selective α1‑adrenergic receptor agonist, causing vasoconstriction of nasal mucosal vessels and reducing congestion. Paracetamol inhibits central cyclo‑oxygenase enzymes, providing analgesic and antipyretic effects. Caffeine antagonises adenosine receptors, producing mild central nervous system stimulation and enhancing the analgesic action of paracetamol.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Dizziness: transient light‑headedness reported.
  • Insomnia: difficulty sleeping, especially with the day formulation.
  • Dry mouth: reduced salivation.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, breathing difficulty.
  • Elevated blood pressure: significant rise in systolic or diastolic pressure.

Precautions & Warnings

Before using this product, consider the following precautions:

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use only if the benefits outweigh potential risks.
  • Hypertension: avoid or use under medical supervision due to phenylephrine.
  • Liver disease: limit use because of paracetamol content.
  • Concomitant MAO inhibitors: avoid because of caffeine interaction.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Max Strength Cold & Flu Day & Night may interact with other medicines as follows:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis with caffeine.
  • Other sympathomimetic decongestants (e.g., pseudoephedrine): additive vasoconstrictive effects.
  • Additional paracetamol‑containing products: risk of hepatic overdose.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may diminish phenylephrine’s decongestant effect.
  • Antihypertensive agents: phenylephrine may counteract blood‑pressure control.
  • CYP1A2 inhibitors (e.g., fluvoxamine): may increase caffeine levels.

Frequently Asked Questions

Max Strength Cold & Flu Day & Night is an over‑the‑counter oral tablet that combines phenylephrine, paracetamol and caffeine to provide temporary relief of nasal congestion, fever, headache, sore throat and general aches associated with the common cold and influenza.

Phenylephrine is a selective α1‑adrenergic receptor agonist. By stimulating these receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which reduces swelling and opens the nasal passages, helping to alleviate congestion.

The appropriate dose is determined by the prescribing healthcare professional or according to the product label. Patients should follow the specific instructions provided by their doctor or pharmacist and not exceed the recommended amount.

Pregnant or breastfeeding individuals should consult their healthcare provider before using this product. The provider will weigh the potential benefits against any possible risks to the mother and infant, especially considering phenylephrine and caffeine.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient formulations, Max Strength Cold & Flu Day & Night offers a three‑component approach: phenylephrine for decongestion, paracetamol for pain and fever, and caffeine for mild stimulation. This combination can reduce the need for multiple separate products, but individual tolerability and contraindications must be considered.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

The medication is taken orally with a full glass of water. It is intended for short‑term use during an episode of cold or flu symptoms. Patients should not crush or chew the tablets unless the label specifically permits it.

Serious risks include severe allergic reactions such as anaphylaxis and significant increases in blood pressure, especially in individuals with pre‑existing hypertension. Prompt medical attention is required if symptoms like rash, swelling, difficulty breathing, or a sudden rise in blood pressure occur.

Individuals with known hypersensitivity to phenylephrine, paracetamol, caffeine or any excipients should avoid this product. It is also contraindicated in patients with uncontrolled hypertension, severe liver disease, or those taking monoamine oxidase inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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