Product image of Max Strength Cold & Flu Day & Night (Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Max Strength Cold & Flu Day & Night

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Max Strength Cold & Flu Day & Night (Phenylephrine Hydrochloride, Paracetamol | Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, Paracetamol and Caffeine, the active ingredients in Max Strength Cold & Flu Day & Night, are a sympathomimetic decongestant, analgesic, antipyretic and CNS stimulant presented as a max‑strength tablet for oral use. It provides temporary relief of nasal congestion, fever, headache, body aches and fatigue associated with common cold or influenza in adults.

GNH India supplies Max Strength Cold & Flu Day & Night as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Max Strength Cold & Flu Day & Night combines phenylephrine, paracetamol and caffeine to target the symptom complex of upper respiratory viral infections.

  • Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
  • Fever: lowers elevated body temperature through central prostaglandin inhibition.
  • Headache: alleviates pain by acting on central pain pathways.
  • Body aches and pains: provides analgesic relief for muscular discomfort.
  • Fatigue: counteracts drowsiness and promotes alertness via caffeine stimulation.

How It Works

  • Phenylephrine acts as an alpha‑adrenergic agonist, causing vasoconstriction of nasal mucosal vessels and decreasing congestion. Paracetamol inhibits central cyclooxygenase‑mediated prostaglandin synthesis, producing analgesic and antipyretic effects. Caffeine antagonises adenosine receptors, resulting in mild central nervous system stimulation and potentiation of analgesia. The combined actions address multiple cold and flu symptoms through complementary pharmacologic pathways.

Side Effects

Adverse reactions to Max Strength Cold & Flu Day & Night are generally mild but may vary among individuals.

Common Side Effects

  • Nausea
  • Dizziness
  • Insomnia
  • Increased heart rate
  • Dry mouth
  • Mild headache

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypertension
  • Cardiac arrhythmia
  • Hepatotoxicity
  • Seizures
  • Stevens‑Johnson syndrome

Precautions & Warnings

Before using Max Strength Cold & Flu Day & Night, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Liver disease: avoid or use with caution due to paracetamol content.
  • Hypertension: phenylephrine may raise blood pressure.
  • Drug interactions: review all concomitant medications.
  • Age: not recommended for children under 12 without medical advice.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Max Strength Cold & Flu Day & Night may interact with other medicines; assess the level of risk.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors: risk of hypertensive crisis.
  • Other sympathomimetic agents (e.g., pseudoephedrine): may cause excessive vasoconstriction.
  • Triptans: potential for serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Additional caffeine‑containing products: may increase nervous system stimulation.
  • Antihypertensive drugs: phenylephrine may reduce their effectiveness.
  • Alcohol: can enhance liver load and increase risk of hepatotoxicity.

Frequently Asked Questions

Max Strength Cold & Flu Day & Night is an over‑the‑counter oral tablet that combines phenylephrine, paracetamol and caffeine to provide temporary relief of nasal congestion, fever, headache, body aches and fatigue associated with common cold or influenza in adults.

Phenylephrine constricts nasal blood vessels, reducing congestion. Paracetamol blocks central prostaglandin production, lowering fever and relieving pain. Caffeine blocks adenosine receptors, offering mild stimulation and enhancing the analgesic effect of paracetamol, resulting in broader symptom control.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s age, weight, medical condition and other medications. Patients should follow the prescriber’s instructions and the product label.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this product.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient decongestants or analgesics, Max Strength Cold & Flu Day & Night offers a combined approach: phenylephrine for congestion, paracetamol for pain and fever, and caffeine for fatigue. This multi‑symptom coverage can reduce the need for multiple separate products.

Store at ambient temperature: keep the tablets in the original packaging, protect them from moisture and excessive heat, and keep them out of reach of children.

The product is taken orally with a full glass of water. It is intended for short‑term use to relieve cold and flu symptoms; the exact dosing schedule should follow the prescriber’s guidance and the label instructions.

Serious risks include severe allergic reactions (anaphylaxis), marked hypertension, cardiac arrhythmias, liver injury from paracetamol overdose, and rare severe skin reactions such as Stevens‑Johnson syndrome. Seek immediate medical attention if any of these occur.

Individuals with known hypersensitivity to phenylephrine, paracetamol, caffeine or any excipients, patients with uncontrolled hypertension, severe liver disease, or those taking MAO inhibitors should avoid this product unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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