Product image of Maxalt (Rizatriptan Benzoate) supplied by GNH India

Maxalt

Active Ingredient:
Rizatriptan Benzoate
Origin:
EU

Maxalt (Rizatriptan Benzoate)

Rizatriptan, the active ingredient in Maxalt, is a triptan presented as an oral tablet for oral use. It is used for the acute treatment of migraine attacks in adults, with or without aura.
GNH India supplies Maxalt as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

N.V. Organon

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Maxalt belongs to the triptan class and is used to treat migraine-related pathways.
  • Migraine with aura: provides rapid relief of headache and associated symptoms.
  • Migraine without aura: aborts an ongoing migraine attack.
  • Migraine-associated symptoms: reduces nausea, vomiting, photophobia and phonophobia during an attack.

How It Works

  • Rizatriptan acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on intracranial blood vessels and trigeminal nerve terminals. Activation causes cranial vasoconstriction and inhibits the release of vasoactive neuropeptides, thereby interrupting the migraine pain cascade.

Side Effects

Common Side Effects

  • Taste disturbance
  • Dizziness
  • Fatigue
  • Dry mouth
  • Nausea
  • Tingling sensation

Serious or Rare Side Effects

  • Chest pain or tightness
  • Severe hypertension
  • Serotonin syndrome
  • Allergic reactions, including anaphylaxis
  • Cardiac arrhythmia
  • Ischemic events

Precautions & Warnings

  • Before prescribing Maxalt, consider the following precautions.
  • Cardiovascular disease: avoid use in patients with uncontrolled hypertension or coronary artery disease.
  • History of stroke: contraindicated in individuals with recent cerebrovascular events.
  • Concomitant serotonergic drugs: increased risk of serotonin syndrome; assess medication history.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Drug interactions: review all current medications before initiating therapy.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Rizatriptan may interact with several drug classes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension.
  • Ergot derivatives: increased vasospasm risk.
  • Other triptans: cumulative serotonergic effect.
  • SSRIs/SNRIs: potential serotonin syndrome.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): elevate rizatriptan levels.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin): may reduce efficacy.
  • Beta‑blockers: may enhance hypotensive effect.
  • Antihypertensives: monitor blood pressure response.

Frequently Asked Questions

Maxalt contains rizatriptan and is indicated for the acute treatment of migraine attacks, with or without aura, in adult patients. It helps relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia.

Rizatriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of intracranial arteries and blocks the release of pain‑triggering neuropeptides, interrupting the migraine cascade.

The prescribed dose is determined by the treating physician based on individual response and tolerability. Typically, a single oral tablet is taken at the onset of migraine symptoms, with a possible second dose after a specified interval if needed, but exact dosing must follow the prescriber’s instructions.

Safety data for rizatriptan in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Maxalt (rizatriptan) has a rapid onset of action, usually within 30 minutes, and a relatively short half‑life compared with some other triptans such as sumatriptan or naratriptan. Efficacy and tolerability are comparable, but individual response varies, so clinicians may choose based on patient history and preference.

Maxalt tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiration date.

Maxalt is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably at the first sign of a migraine attack. Do not crush, chew, or split the tablet unless specifically instructed by a healthcare provider.

Serious adverse events, although rare, include chest pain or tightness, severe hypertension, serotonin syndrome when combined with other serotonergic agents, and allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if any of these symptoms occur.

Maxalt is contraindicated in patients with uncontrolled hypertension, a history of coronary artery disease, recent myocardial infarction or stroke, peripheral vascular disease, and in those taking ergot derivatives or other triptans. It should also be avoided in individuals with known hypersensitivity to rizatriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.