Product image of Maxeeze (Paracetamol, Caffeine, Codeine Phosphate Hemihydrate) supplied by GNH India

Maxeeze

Active Ingredient:
Paracetamol, Caffeine, Codeine Phosphate Hemihydrate
Origin:
EU

Maxeeze (Paracetamol, Caffeine, Codeine Phosphate Hemihydrate)

Paracetamol, caffeine and codeine phosphate hemihydrate, the active ingredients in Maxeeze, are analgesic and antipyretic agents presented as oral tablets for adult use. They provide relief of mild to moderate pain, headache and fever in patients requiring combined analgesic therapy.

GNH India supplies Maxeeze as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zentiva, K.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Maxeeze combines paracetamol, caffeine and codeine to target pain and fever pathways.

  • Mild to moderate pain: provides analgesic relief through synergistic action of the three components.
  • Headache: reduces headache intensity by acting on central pain mechanisms.
  • Fever: lowers elevated body temperature by inhibiting prostaglandin synthesis.

How It Works

  • Paracetamol inhibits cyclooxygenase enzymes, reducing prostaglandin production and lowering pain and temperature. Caffeine antagonises adenosine receptors, enhancing central analgesia and counteracting drowsiness. Codeine phosphate hemihydrate acts as a μ‑opioid receptor agonist, providing opioid‑mediated analgesia and modest antitussive effects. The combination yields additive pain relief and antipyretic activity.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Drowsiness: increased sleepiness, especially after the first dose.
  • Constipation: reduced bowel movements.
  • Dizziness: transient light‑headedness.
  • Dry mouth: reduced salivation.
  • Loss of appetite: decreased hunger.

Serious or Rare Side Effects

  • Respiratory depression: slowed breathing, especially with high opioid exposure.
  • Dependence or addiction: risk of misuse with prolonged use.
  • Severe allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Hepatotoxicity: liver injury if paracetamol dose exceeds safe limits.
  • Opioid‑induced constipation leading to bowel obstruction.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: rare severe skin reactions.

Precautions & Warnings

Before using Maxeeze, consider the following precautions.

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Respiratory disorders: use with caution in patients with asthma or COPD due to opioid‑related breathing effects.
  • Alcohol consumption: avoid concurrent intake as it may increase sedation and liver risk.
  • Driving or operating machinery: may cause drowsiness; refrain until the effect is known.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Maxeeze may interact with several medicines; review the following categories.

Major Interactions (Avoid)

  • Other opioids: additive respiratory depression and sedation.
  • MAO inhibitors: risk of severe sedation and hypotension.
  • Central nervous system depressants (e.g., benzodiazepines): heightened drowsiness.
  • Alcohol: enhanced CNS depression and liver strain.
  • Anticholinergic agents: increased risk of constipation.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): possible serotonin syndrome.
  • Diuretics: may exacerbate urinary retention.
  • Antihistamines: additive sedative effects.
  • CYP2D6 inhibitors: may alter codeine metabolism and efficacy.
  • Anticoagulants: potential for altered bleeding risk due to paracetamol.

Frequently Asked Questions

Maxeeze is a prescription oral tablet that combines paracetamol, caffeine and codeine phosphate hemihydrate to treat mild to moderate pain, headache and fever. The three ingredients work together to provide faster and more effective relief than a single agent alone.

Paracetamol reduces pain and fever by inhibiting cyclooxygenase enzymes and lowering prostaglandin synthesis. Caffeine blocks adenosine receptors, which enhances the analgesic effect and reduces drowsiness. Codeine acts as a μ‑opioid receptor agonist, providing opioid‑mediated pain relief. Together they give additive analgesia and antipyretic action.

The specific dose of Maxeeze is determined by the prescribing clinician based on the patient’s age, weight, severity of symptoms and other medical factors. Healthcare professionals adjust the regimen to achieve optimal pain or fever control while minimizing risk.

Safety data for Maxeeze in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using this medication.

To request Maxeeze, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient paracetamol or ibuprofen, Maxeeze adds caffeine and codeine, which can produce faster and stronger analgesia for moderate pain. Unlike pure opioid products, the presence of paracetamol and caffeine may reduce the required opioid dose, potentially lowering the risk of dependence.

Maxeeze tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from moisture and direct sunlight, and keep out of reach of children.

Maxeeze is taken orally with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless a healthcare professional advises otherwise. It is usually taken as needed for pain or fever, following the prescriber’s instructions.

The most serious risks include respiratory depression, especially in patients with underlying lung disease or when combined with other depressants, and the potential for dependence or misuse due to the codeine component. Severe allergic reactions and liver injury from excessive paracetamol are also critical concerns.

Maxeeze should be avoided in individuals with known hypersensitivity to any of its ingredients, severe respiratory disorders, significant liver impairment, or a history of opioid addiction. It is also contraindicated in patients taking MAO inhibitors or other medications that may cause dangerous interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Paracetamol, Caffeine, Codeine Phosphate Hemihydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT