Product image of Maxicortan (Hydrocortisone Acetate) supplied by GNH India

Maxicortan

Active Ingredient:
Hydrocortisone Acetate
Origin:
EU

Maxicortan (Hydrocortisone Acetate)

Hydrocortisone acetate, the active ingredient in Maxicortan, is a corticosteroid presented as a topical formulation for skin application. It is used to reduce inflammation and relieve itching in various dermatologic conditions, particularly in adults and children with inflammatory skin disorders.

GNH India supplies Maxicortan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aflofarm Farmacja Polska Sp. Z O.O.

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Indications & Clinical Uses

Maxicortan, a topical corticosteroid, is employed in the management of inflammatory skin diseases.

  • Eczema: reduces redness, swelling and pruritus associated with atopic dermatitis.
  • Contact dermatitis: alleviates inflammation and itching caused by irritant or allergic reactions.
  • Psoriasis: softens plaques and diminishes scaling and discomfort.
  • Other inflammatory skin disorders: provides symptomatic relief in conditions such as seborrheic dermatitis and lichen planus.

How It Works

  • Hydrocortisone acetate penetrates the epidermis and binds to intracellular glucocorticoid receptors. The drug‑receptor complex translocates to the nucleus, where it modulates gene transcription, suppressing pro‑inflammatory cytokines and mediators while enhancing anti‑inflammatory protein synthesis, resulting in reduced edema, erythema and immune cell activity at the site of application.

Side Effects

Topical hydrocortisone acetate may cause local and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Skin irritation or burning sensation at the application site.
  • Pruritus or itching.
  • Dryness or flaking of the skin.
  • Redness (erythema).
  • Folliculitis or mild acneiform eruptions.
  • Mild hyperpigmentation.

Serious or Rare Side Effects

  • Allergic contact dermatitis.
  • Skin atrophy or thinning with prolonged use.
  • Secondary bacterial, fungal or viral infection.
  • Systemic adrenal suppression, especially with extensive application.
  • Hypersensitivity reactions such as urticaria.
  • Delayed wound healing.

Precautions & Warnings

When using Maxicortan, consider the following safety measures.

  • Avoid use on broken or infected skin: may increase systemic absorption and infection risk.
  • Limit duration of therapy: prolonged use can cause skin atrophy.
  • Use the smallest effective amount: reduces risk of systemic effects.
  • Monitor for signs of adrenal suppression: especially in children or extensive application.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Topical hydrocortisone acetate can interact with other agents, affecting safety or efficacy.

Major Interactions (Avoid)

  • Systemic glucocorticoids: additive immunosuppressive effects may increase infection risk.
  • Live vaccines: immunosuppression may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Potent CYP3A4 inhibitors (e.g., ketoconazole): may increase local steroid concentration.
  • Occlusive dressings: enhance percutaneous absorption, raising systemic exposure.
  • Photosensitizing drugs (e.g., tetracyclines): may increase risk of photosensitivity reactions.

Frequently Asked Questions

Maxicortan is a topical corticosteroid indicated for the relief of inflammation, redness and itching associated with eczema, contact dermatitis, psoriasis and other inflammatory skin disorders. It helps improve skin appearance and comfort by reducing the underlying immune response.

Hydrocortisone acetate binds to glucocorticoid receptors inside skin cells, altering gene transcription. This action suppresses the production of pro‑inflammatory cytokines and mediators while promoting anti‑inflammatory proteins, leading to decreased swelling, erythema and immune cell activity at the site of application.

The appropriate amount and frequency of Maxicortan are determined by the prescribing healthcare professional based on the severity of the skin condition, patient age and treatment area. Patients should follow the prescriber’s instructions and not exceed the recommended application.

Safety data for topical hydrocortisone acetate in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To request Maxicortan, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Maxicortan contains hydrocortisone acetate, a low‑ to medium‑potency corticosteroid. Compared with higher‑potency agents such as clobetasol, it offers a favorable safety profile for short‑term use on sensitive areas, while still providing effective anti‑inflammatory action for mild to moderate skin conditions.

Store Maxicortan at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Maxicortan is applied topically to the affected skin area. A thin layer should be spread gently and rubbed in until absorbed, typically once or twice daily as directed by the prescriber. Hands should be washed before and after application.

Serious risks include skin atrophy, secondary infections, allergic contact dermatitis and, with extensive or prolonged use, systemic adrenal suppression. Patients should report any unusual skin changes, signs of infection or systemic symptoms such as fatigue or dizziness to their healthcare provider.

Maxicortan should be avoided in individuals with known hypersensitivity to hydrocortisone acetate or any formulation components, on severely infected or ulcerated skin, and in patients receiving systemic corticosteroids where additive effects could be harmful, unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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