Product image of Maxilene (Lidocaine) supplied by GNH India

Maxilene

Active Ingredient:
Lidocaine
Origin:
EU

Maxilene (Lidocaine)

Lidocaine, the active ingredient in Maxilene, is a local anesthetic presented as a topical preparation for skin application. It provides temporary loss of sensation and pain relief for minor skin irritations and procedures. Maxilene is intended for use on intact skin and is commonly employed in clinical and pharmacy settings.

GNH India supplies Maxilene as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ferndale Laboratories Limited

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Indications & Clinical Uses

Maxilene, a topical lidocaine product, works on peripheral nerve endings to provide local anesthesia and pain relief.

  • Local skin anesthesia: produces temporary numbness for minor dermatologic procedures.
  • Minor skin irritation pain relief: eases discomfort from insect bites, abrasions, or mild burns.
  • Superficial dermatologic procedures: facilitates painless application of topical treatments during skin care or minor surgical interventions.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, stabilizing the neuronal membrane and preventing the initiation and propagation of action potentials. This inhibition of sodium influx halts nerve impulse transmission, resulting in localized loss of sensation and analgesia at the site of application.

Side Effects

Topical lidocaine may cause a range of skin‑related and systemic reactions.

Common Side Effects

  • Localized burning or stinging sensation.
  • Mild erythema or redness at the application site.
  • Pruritus or itching.
  • Transient numbness extending slightly beyond the treated area.
  • Contact dermatitis in sensitive individuals.
  • Minor swelling or edema.

Serious or Rare Side Effects

  • Systemic toxicity presenting as dizziness, tinnitus, or seizures.
  • Cardiac arrhythmias or conduction disturbances.
  • Severe allergic reactions including angioedema or anaphylaxis.
  • Methemoglobinemia causing cyanosis.
  • Persistent numbness or motor weakness.
  • Necrosis of skin with excessive or prolonged use.

Precautions & Warnings

When using Maxilene, consider the following safety measures.

  • Assess skin integrity: avoid application on broken, infected, or inflamed skin.
  • Check for lidocaine allergy: discontinue use if hypersensitivity signs appear.
  • Limit area of application: do not exceed recommended surface area to reduce systemic absorption.
  • Avoid concurrent use with other topical anesthetics: may increase risk of toxicity.
  • Pregnancy category B1: use only when benefit outweighs potential risk.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lidocaine may interact with other medications, requiring attention to potential additive effects.

Major Interactions (Avoid)

  • Other amide‑type local anesthetics: concurrent use can increase systemic toxicity.
  • Class I antiarrhythmic drugs (e.g., quinidine, procainamide): may cause additive cardiac effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask early signs of lidocaine toxicity.
  • CYP3A4 inhibitors: can modestly raise lidocaine plasma levels.
  • Alcohol: may enhance central nervous system depression when combined with lidocaine.

Frequently Asked Questions

Maxilene is a topical formulation containing lidocaine that is used to provide local anesthesia of the skin and to relieve pain associated with minor skin irritations such as insect bites, abrasions, or superficial dermatologic procedures.

Lidocaine works by blocking voltage‑gated sodium channels on peripheral nerves, which prevents the initiation and propagation of nerve impulses. This interruption of signal transmission results in temporary loss of sensation and analgesia at the site where the product is applied.

The appropriate amount of Maxilene to apply is determined by the prescribing healthcare professional based on the size of the area to be treated, the condition being addressed, and patient‑specific factors. Patients should follow the prescriber’s instructions and not exceed the recommended surface area.

Maxilene is classified as pregnancy category B1, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It may be used during pregnancy or lactation only if the potential benefit justifies any potential risk, and this decision should be made by a qualified healthcare provider.

To order Maxilene, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After receiving the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with other topical anesthetics such as benzocaine or prilocaine, lidocaine in Maxilene typically offers a faster onset of action and a well‑established safety profile. It provides effective surface anesthesia for a broad range of minor skin procedures, while the risk of allergic reactions is generally lower than with some ester‑type anesthetics.

Maxilene should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Ensure the container is tightly closed when not in use to maintain product stability and potency.

Maxilene is applied topically to clean, intact skin. A thin layer is spread over the affected area using a gloved fingertip or applicator, as directed by the prescriber. The product should be left in place for the recommended duration before removal or before proceeding with the intended procedure.

The most serious risks include systemic lidocaine toxicity, which can manifest as neurological symptoms (e.g., dizziness, seizures) or cardiac disturbances (e.g., arrhythmias). Severe allergic reactions such as anaphylaxis and rare cases of methemoglobinemia are also possible and require immediate medical attention.

Maxilene should not be used on patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, on broken or infected skin, or in individuals where the prescribed surface area exceeds safety limits. Caution is also advised for patients with significant cardiac, hepatic, or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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