Product image of Maxilin (Clarithromycin) supplied by GNH India

Maxilin

Active Ingredient:
Clarithromycin
Origin:
EU

Maxilin (Clarithromycin)

Clarithromycin, the active ingredient in Maxilin, is a macrolide antibiotic presented as a / for oral use. It treats bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and is part of Helicobacter pylori eradication regimens.

GNH India supplies Maxilin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Anfarm Hellas Sa

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Indications & Clinical Uses

Clarithromycin is a macrolide antibiotic used to treat bacterial infections in various organ systems.

  • Community‑acquired pneumonia: clears the causative bacteria and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and infection symptoms.
  • Acute bacterial exacerbations of chronic bronchitis: shortens illness duration and improves airflow.
  • Skin and soft‑tissue infections: eradicates susceptible skin pathogens.
  • Helicobacter pylori eradication regimens: contributes to bacterial eradication when combined with other agents.

How It Works

  • Clarithromycin binds to the 50S subunit of bacterial ribosomes, inhibiting translocation of the peptidyl‑tRNA. This blocks protein synthesis, leading to a bacteriostatic effect against susceptible organisms and, at higher concentrations, a bactericidal effect.

Side Effects

Clarithromycin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Diarrhea: frequent loose stools.
  • Abdominal pain: cramping or discomfort.
  • Taste disturbance: altered or metallic taste.
  • Headache: mild to moderate.
  • Vomiting: occasional episodes.

Serious or Rare Side Effects

  • QT prolongation: risk of cardiac arrhythmias.
  • Severe allergic reaction: anaphylaxis, rash, or swelling.
  • Clostridioides difficile infection: severe colitis.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Cardiac arrhythmia: irregular heartbeat beyond QT issues.

Precautions & Warnings

Before prescribing clarithromycin, clinicians should consider several safety measures.

  • Assess liver function: monitor hepatic enzymes before and during therapy.
  • Review concomitant medications: check for potential drug‑drug interactions.
  • Use caution in patients with QT prolongation: obtain baseline ECG.
  • Avoid in known macrolide hypersensitivity: discontinue if rash or angioedema occurs.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Clarithromycin interacts with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Cisapride: may cause serious cardiac arrhythmias.
  • Pimozide: increased plasma concentrations leading to toxicity.
  • Ergot alkaloids: risk of ergotism and severe vasospasm.

Moderate Interactions (Monitor Closely)

  • Warfarin: may increase INR and bleeding risk.
  • Theophylline: may raise serum levels causing toxicity.
  • Statins (e.g., simvastatin): may increase risk of myopathy.

Frequently Asked Questions

Maxilin contains clarithromycin, a macrolide antibiotic indicated for community‑acquired pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, skin and soft‑tissue infections, and as part of combination therapy for Helicobacter pylori eradication.

Clarithromycin binds to the bacterial 50S ribosomal subunit, blocking the translocation step of protein synthesis. This inhibition stops bacterial growth (bacteriostatic) and, at higher concentrations, can kill susceptible organisms (bactericidal).

The specific dose of Maxilin is determined by the prescribing clinician based on the infection being treated, patient age, weight, renal and hepatic function, and local guidelines. Patients should follow the prescriber’s instructions precisely.

Clarithromycin’s safety in pregnancy is not well established, and it is classified as a pregnancy category where benefits must outweigh potential risks. It is excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before use.

To order Maxilin, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Clarithromycin, the active ingredient in Maxilin, has a broader spectrum against certain atypical pathogens compared with erythromycin and offers better gastric stability than azithromycin. However, drug‑interaction potential and QT‑prolongation risk are higher, requiring careful patient selection.

Maxilin should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Do not store in humid environments such as bathrooms.

Maxilin is taken orally, usually with or without food as directed by the prescriber. The tablets should be swallowed whole with a full glass of water and not crushed or chewed unless specifically instructed.

Serious risks include QT interval prolongation leading to potentially life‑threatening arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhea, and hepatic injury. Patients should seek immediate medical attention if they experience palpitations, rash, severe abdominal pain, or jaundice.

Maxilin should not be used by individuals with a known hypersensitivity to clarithromycin or other macrolides, patients taking contraindicated drugs such as cisapride or pimozide, and those with a history of significant QT prolongation unless closely monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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