Product image of Maxim (Dienogest, Ethinylestradiol) supplied by GNH India

Maxim

Active Ingredient:
Dienogest, Ethinylestradiol
Origin:
EU

Maxim (Dienogest, Ethinylestradiol)

Dienogest/Ethinylestradiol, the active ingredient in Maxim, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus.
GNH India supplies Maxim as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Jenapharm Gmbh & Co Kg

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Indications & Clinical Uses

  • Maxim, a combined oral contraceptive, is used to prevent pregnancy by regulating the hormonal cycle.
  • Contraception: prevents pregnancy in women of childbearing potential.
  • Dysmenorrhea: reduces menstrual pain and improves cycle regularity.
  • Acne management: helps control hormonal acne associated with menstrual cycles.

How It Works

  • Dienogest and ethinylestradiol act on the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol provides negative feedback to suppress follicle‑stimulating hormone, while dienogest blocks luteinizing hormone surge, preventing ovulation. The combination also thickens cervical mucus and induces endometrial changes that hinder sperm penetration and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: temporary swelling or discomfort.
  • Spotting: irregular breakthrough bleeding.

Serious or Rare Side Effects

  • Thromboembolic events: deep‑vein thrombosis or pulmonary embolism.
  • Hypertension: significant increase in blood pressure.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before prescribing Maxim, clinicians should evaluate individual risk factors and contraindications.

  • Assess cardiovascular risk: review history of thrombosis, hypertension, smoking.
  • Screen for liver disease: avoid use in active hepatic impairment.
  • Consider smoking status: contraindicated in women over 35 who smoke.
  • Review medication history: avoid concomitant use with strong enzyme inducers.
  • Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.

Avoid Interactions

Maxim may interact with several medicines that alter hormone metabolism.

Major Interactions (Avoid)

  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): reduce contraceptive efficacy.
  • Rifampin: decreases plasma hormone levels, risking breakthrough bleeding.
  • Protease inhibitor antiretrovirals (e.g., ritonavir): may increase risk of thrombotic events.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (e.g., ketoconazole): can raise hormone concentrations.
  • St. John’s wort: may lower effectiveness of the contraceptive.
  • Macrolide antibiotics (e.g., erythromycin): may modestly increase plasma hormone levels.

Frequently Asked Questions

Maxim is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. It works by inhibiting ovulation and creating cervical mucus changes that reduce the likelihood of fertilisation and implantation.

The ethinylestradiol component provides estrogenic feedback that suppresses follicle‑stimulating hormone, while dienogest, a progestogen, blocks the luteinising hormone surge needed for ovulation. Together they also thicken cervical mucus and alter the endometrium, making conception unlikely.

The dosing regimen for Maxim is determined by the prescribing clinician. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and duration are set according to individual medical guidance.

Maxim is intended for use before pregnancy and should be discontinued if pregnancy occurs. Its safety in pregnancy is not established, and it is generally not recommended during breastfeeding without medical advice, as hormonal exposure may affect milk production.

To order Maxim, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Maxim contains dienogest and ethinylestradiol, a formulation known for a lower androgenic profile compared with some older progestins. This may result in fewer acne‑related side effects while providing comparable contraceptive efficacy to other combined oral contraceptives.

Maxim tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and keep out of reach of children.

Maxim is taken orally as a tablet. The usual practice is to swallow one tablet each day, preferably at the same time each day, with or without food, following the cycle prescribed by the healthcare professional.

The most serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe hypertension, and rare allergic reactions. Women with a history of clotting disorders, uncontrolled hypertension, or smoking over age 35 should be evaluated carefully before use.

Maxim is contraindicated in women with known or suspected pregnancy, active liver disease, uncontrolled hypertension, a history of thromboembolic disorders, or in smokers over 35 years of age. It should also be avoided in individuals taking medications that strongly induce hepatic enzymes.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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