Product image of Maxipirin (Acetylsalicylic Acid) supplied by GNH India

Maxipirin

Active Ingredient:
Acetylsalicylic Acid
Origin:
EU

Maxipirin (Acetylsalicylic Acid)

Acetylsalicylic Acid, the active ingredient in Maxipirin, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects and is used in adults for pain, fever, inflammation and cardiovascular event prevention.

GNH India supplies Maxipirin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Dr. Max Pharma S.R.O.

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Indications & Clinical Uses

Maxipirin (acetylsalicylic acid) is used in several therapeutic areas that involve prostaglandin‑mediated processes.

  • Pain relief: reduces mild to moderate pain such as headache, musculoskeletal aches, and dental pain.
  • Fever reduction: lowers elevated body temperature associated with infectious or inflammatory conditions.
  • Inflammation reduction: alleviates inflammatory swelling in conditions like arthritis.
  • Prevention of thrombotic cardiovascular events: inhibits platelet aggregation to lower risk of heart attack and stroke in at‑risk patients.

How It Works

  • Acetylsalicylic acid irreversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins and thromboxane A₂. The reduction in prostaglandins diminishes pain, fever and inflammation, while decreased thromboxane A₂ limits platelet aggregation, providing antiplatelet activity. This enzymatic blockade underlies its analgesic, antipyretic, anti‑inflammatory and antithrombotic properties.

Side Effects

Acetylsalicylic acid may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Gastric irritation: heartburn or gastritis.
  • Minor bleeding: easy bruising or nosebleeds.
  • Headache: transient headache episodes.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding.
  • Allergic reactions: rash, itching, or anaphylaxis.
  • Hepatic or renal impairment: signs of liver or kidney dysfunction.
  • Reye’s syndrome: rare but serious condition in children with viral illness.

Precautions & Warnings

When prescribing or dispensing Maxipirin, several precautions should be observed to minimize risk.

  • Assess gastrointestinal risk: evaluate history of ulcers, bleeding or NSAID use.
  • Evaluate bleeding risk: consider concurrent anticoagulants or clotting disorders.
  • Monitor renal function: avoid in patients with severe kidney impairment.
  • Pregnancy consideration: avoid use in the third trimester due to fetal risks.
  • Contraindications: do not use in individuals with known hypersensitivity to aspirin or other NSAIDs.
  • Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Acetylsalicylic acid can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective COX‑2 inhibitors (e.g., celecoxib): heightened gastrointestinal toxicity.
  • SSRIs or SNRIs: elevated bleeding tendency.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may exacerbate gastric ulcer risk.
  • Diuretics (e.g., thiazides): may reduce renal clearance of aspirin.
  • Methotrexate: aspirin can increase methotrexate toxicity.

Frequently Asked Questions

Maxipirin contains acetylsalicylic acid, an NSAID that provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects. It is commonly employed to relieve mild‑to‑moderate pain, reduce fever, treat inflammatory conditions such as arthritis, and lower the risk of thrombotic cardiovascular events in appropriate adult patients.

Acetylsalicylic acid irreversibly blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, preventing the conversion of arachidonic acid into prostaglandins and thromboxane A₂. The resulting decrease in prostaglandins reduces pain, fever and inflammation, while reduced thromboxane A₂ limits platelet aggregation, giving the drug its antiplatelet activity.

The appropriate dose of Maxipirin is determined by the prescribing healthcare professional based on the specific indication, patient age, weight and clinical condition. Dosage regimens may differ for pain relief, fever management, anti‑inflammatory therapy or cardiovascular prophylaxis, and should always follow the prescriber’s instructions and local labeling.

Maxipirin is classified as pregnancy category D, indicating potential risk to the fetus, especially in the third trimester due to possible effects on the fetal cardiovascular system. Use during pregnancy is generally avoided unless clearly needed. Limited data are available for breastfeeding; caution is advised and a healthcare provider should evaluate the risk‑benefit ratio.

To place an order, submit an enquiry on the Maxipirin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements) and necessary import documentation.

Maxipirin is a generic formulation of acetylsalicylic acid, offering the same pharmacological profile as branded aspirin products. Differences may lie in manufacturing standards, excipients, packaging or regulatory approvals. Clinically, efficacy and safety are comparable when used at equivalent doses, though individual patient tolerance to specific formulations can vary.

Maxipirin should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not store in damp or excessively hot environments, as this may affect tablet integrity.

Maxipirin is taken orally, usually with a full glass of water. It may be swallowed with or without food, although taking it with food can lessen gastrointestinal discomfort. The tablet should not be crushed or chewed unless specifically instructed by a healthcare professional.

The most serious adverse events include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and, in rare cases, Reye’s syndrome in children with viral infections. Additionally, increased bleeding risk can occur when combined with anticoagulants or other antiplatelet agents, requiring careful monitoring.

Maxipirin should be avoided in individuals with a known hypersensitivity to aspirin or other NSAIDs, those with active gastrointestinal ulcer disease, severe renal or hepatic impairment, and in the third trimester of pregnancy. Patients on anticoagulant therapy or with bleeding disorders should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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