Maxitrol (Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone)

Neomycin interferes with bacterial protein synthesis by binding the 30S ribosomal subunit, while polymyxin B disrupts bacterial cell membranes, leading to cell death. Dexamethasone, a glucocorticoid, binds intracellular receptors and modulates gene expression to suppress inflammatory mediators, reducing swelling, redness, and pain in the eye.

The dosing regimen for Maxitrol is determined by the prescribing clinician based on the specific indication, severity of infection, and patient factors. Typically, the medication is instilled as one to two drops in the affected eye(s) at intervals recommended by the eye care professional.

Safety data for Maxitrol in pregnancy and lactation are limited. It should be used only if the potential therapeutic benefit justifies the potential risk to the fetus or infant. Healthcare providers will weigh the risks and benefits before prescribing to pregnant or nursing individuals.

To place an order, submit an enquiry on the Maxitrol product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Maxitrol combines a broad‑spectrum aminoglycoside (neomycin), a membrane‑active antibiotic (polymyxin B), and a potent corticosteroid (dexamethasone). Compared with single‑agent steroid‑antibiotic products, Maxitrol offers a wider antibacterial spectrum and stronger anti‑inflammatory potency, which can be advantageous in mixed‑infection or severe inflammatory cases.

Store Maxitrol at room temperature, preferably below 25 °C, in its original container. Protect the suspension from light and moisture, and keep the cap tightly closed when not in use. Do not freeze the product, and discard any solution that appears discolored or contains particles.

Maxitrol is applied topically to the eye as an ophthalmic suspension. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. The eye should be gently closed for a few seconds to allow absorption, avoiding blinking or wiping the excess.

Serious risks include allergic reactions such as angioedema or severe eye irritation, secondary ocular infections or corneal ulceration, and a significant rise in intra‑ocular pressure that could lead to glaucoma. Prolonged systemic absorption of dexamethasone may also cause adrenal suppression. Patients should report any worsening vision, pain, or swelling promptly.

Maxitrol is contraindicated in individuals with known hypersensitivity to neomycin, polymyxin B, dexamethasone, or any other component of the formulation. It should also be avoided in patients with active viral or fungal eye infections, uncontrolled glaucoma, or ocular conditions where steroid use is prohibited, unless specifically directed by an eye specialist.