Product image of Maxitrol (Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone) supplied by GNH India

Maxitrol

Active Ingredient:
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Origin:
EU

Maxitrol (Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone)

Neomycin sulfate, Polymyxin B sulfate and Dexamethasone, the active ingredients in Maxitrol, are a combination antibiotic and corticosteroid presented as a 3.5 mg/mL neomycin, 10,000 IU/mL polymyxin B and 0.1 % dexamethasone ophthalmic suspension for topical ocular use. It treats bacterial eye infections with an inflammatory component in patients requiring prescription therapy.

GNH India supplies Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Novartis Pharma N.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Maxitrol is used for ocular infections and inflammatory conditions where bacterial contamination and inflammation coexist.

  • Bacterial conjunctivitis: reduces bacterial load and alleviates conjunctival inflammation.
  • Keratitis: eradicates pathogenic bacteria and diminishes corneal swelling.
  • Post‑operative ocular inflammation: controls inflammation while preventing infection after eye surgery.
  • Anterior uveitis: suppresses intra‑ocular inflammation and limits bacterial involvement.
  • Other ocular infections with inflammatory component: provides broad‑spectrum antibacterial coverage together with anti‑inflammatory action.

How It Works

  • Neomycin binds the 30S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis; Polymyxin B interacts with bacterial cell‑membrane phospholipids, disrupting membrane integrity and causing cell death; Dexamethasone activates intracellular glucocorticoid receptors, modulating gene transcription to suppress pro‑inflammatory cytokines, reduce vascular permeability, and limit leukocyte migration, thereby providing anti‑inflammatory and immunosuppressive effects in ocular tissues.

Side Effects

Adverse ocular reactions may occur with topical use of Maxitrol.

Common Side Effects

  • Eye irritation or burning sensation.
  • Stinging or mild pain upon instillation.
  • Transient blurred vision.
  • Increased intra‑ocular pressure (mild).
  • Conjunctival hyperemia.

Serious or Rare Side Effects

  • Allergic contact dermatitis or severe hypersensitivity reaction.
  • Corneal ulceration or secondary infection.
  • Marked rise in intra‑ocular pressure leading to glaucoma.
  • Vision loss or severe visual impairment.
  • Persistent ocular pain or photophobia.

Precautions & Warnings

Use Maxitrol only under medical supervision and observe the following precautions.

  • Pregnancy: safety not established; avoid unless clearly needed.
  • Breastfeeding: unknown risk; consider potential exposure to the infant.
  • Contact lens wearers: remove lenses before instillation and wait before reinserting.
  • Concurrent ocular steroids: monitor intra‑ocular pressure regularly.
  • Prolonged use: may increase risk of secondary infections or cataract formation.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Maxitrol may interact with other ophthalmic agents; consider the following.

Major Interactions (Avoid)

  • Systemic corticosteroids: additive immunosuppression may increase infection risk.
  • Other ophthalmic antibiotics: potential antagonism or cumulative toxicity.
  • Anticholinergic eye drops: may reduce therapeutic efficacy.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may heighten ocular irritation.
  • Glaucoma medications: monitor intra‑ocular pressure for additive effects.
  • Antiviral eye preparations: assess for reduced antiviral activity.

Frequently Asked Questions

Maxitrol is prescribed for bacterial eye infections that involve inflammation, such as bacterial conjunctivitis, keratitis, post‑operative ocular inflammation, anterior uveitis, and other ocular infections where an anti‑infective and anti‑inflammatory approach is required.

Neomycin inhibits bacterial protein synthesis by binding the 30S ribosomal subunit, while polymyxin B disrupts bacterial cell‑membrane integrity, leading to rapid bacterial death. Dexamethasone activates glucocorticoid receptors, suppressing inflammatory mediators and reducing ocular swelling and redness.

The dosing regimen for Maxitrol is determined by the prescribing ophthalmologist based on the specific infection, severity, and patient factors. The prescriber will provide instructions on the number of drops, frequency, and duration of therapy.

Safety data for Maxitrol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Maxitrol product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑agent ophthalmic antibiotics, Maxitrol offers a broader antibacterial spectrum through neomycin and polymyxin B, plus the added anti‑inflammatory benefit of dexamethasone. This dual action can simplify therapy for infections with significant inflammation, but it also requires careful monitoring for steroid‑related side effects.

Maxitrol should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any remaining product after the indicated period once opened.

Maxitrol is applied as an ophthalmic suspension. The patient instills the prescribed number of drops into the affected eye(s) using the provided dropper, typically after washing hands and avoiding contact between the tip and the eye or surrounding surfaces.

Serious risks include severe allergic reactions, corneal ulceration, marked increase in intra‑ocular pressure that may lead to glaucoma, and rare cases of vision loss. Patients should report any worsening pain, redness, or visual changes immediately.

Maxitrol should be avoided in individuals with known hypersensitivity to neomycin, polymyxin B, dexamethasone, or any component of the formulation. It is also contraindicated in patients with viral eye infections such as herpes simplex keratitis, where steroids could exacerbate the disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT