Maxivalen (Olive Oil, Refined, Soya-Bean Oil Refined, Triglycerides, Medium Chain, Fish Oil, Rich In Omega-3-Ac)

Maxivalen is used in the context of parenteral nutrition to supply energy and essential fatty acids to patients who cannot receive enteral feeding.

• Parenteral nutrition: supplies caloric energy and essential fatty acids for patients unable to tolerate oral or tube feeding.
• Critical care: supports metabolic demands of intensive care patients when enteral routes are contraindicated.
• Post‑operative care: maintains nutritional status in surgical patients with delayed gastrointestinal function.

• Maxivalen delivers a sterile intravenous lipid emulsion containing long‑chain and medium‑chain triglycerides, as well as omega‑3 fatty acids. After infusion, the triglycerides are hydrolyzed by lipases to free fatty acids, which are oxidized for energy or incorporated into cell membranes, while essential fatty acids support membrane integrity and inflammatory modulation, thereby meeting the caloric and lipid requirements of parenteral nutrition.

Adverse reactions may occur with any intravenous lipid emulsion. Monitoring and appropriate management are essential.

Common Side Effects

• Hypertriglyceridemia: elevated serum triglyceride levels during therapy.
• Fever or chills: transient temperature rise during infusion.
• Infusion site erythema: redness or irritation at the catheter site.
• Mild hepatic enzyme elevation: temporary increase in liver function tests.

Serious or Rare Side Effects

• Fat overload syndrome: severe metabolic disturbance with high triglycerides and hepatic dysfunction.
• Acute respiratory distress: rare pulmonary complications linked to lipid emboli.
• Anaphylactoid reaction: severe hypersensitivity requiring immediate medical intervention.

Prior to initiating Maxivalen, clinicians should assess patient-specific risk factors and monitor relevant parameters.

• Monitor triglyceride levels: check serum triglycerides regularly to avoid hypertriglyceridemia.
• Assess liver function: periodic liver enzyme tests are recommended.
• Evaluate for fat overload syndrome: watch for signs of metabolic imbalance.
• Use aseptic technique: ensure sterile handling of the infusion set and solution.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Maxivalen may interact with other agents that affect lipid metabolism or coagulation.

Major Interactions (Avoid)

• Concurrent lipid emulsions: risk of cumulative fat load.
• Propofol infusion: additive hypertriglyceridemia potential.
• High‑dose heparin therapy: may exacerbate triglyceride elevation.

Moderate Interactions (Monitor Closely)

• Warfarin: possible alteration of vitamin K‑dependent clotting factors.
• Certain antibiotics (e.g., ceftriaxone): increased risk of phlebitis.
• Systemic corticosteroids: may raise serum lipid concentrations.