Product image of Mayra (Dienogest, Ethinylestradiol) supplied by GNH India

Mayra

Active Ingredient:
Dienogest, Ethinylestradiol
Origin:
EU

Mayra (Dienogest, Ethinylestradiol)

Dienogest/Ethinylestradiol, the active ingredient in Mayra, is a combined oral contraceptive presented as an oral tablet for oral use. It provides hormonal contraception and helps regulate menstrual cycles in women of reproductive age.

GNH India supplies Mayra as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Exeltis Germany Gmbh

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Indications & Clinical Uses

Mayra is a combined hormonal contraceptive that acts on the reproductive hormone pathway to prevent pregnancy and manage menstrual disorders.

  • Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus.
  • Regulation of menstrual cycles: reduces irregular bleeding and provides predictable cycle control.
  • Management of dysmenorrhea: alleviates painful menstrual cramps through hormonal stabilization.

How It Works

  • Mayra combines dienogest, a progestogenic agent, with ethinylestradiol, an estrogenic compound. The estrogen suppresses follicle‑stimulating hormone (FSH) release, while the progestogen inhibits luteinizing hormone (LH) surge, preventing ovulation. Together they thicken cervical mucus and induce endometrial changes that reduce the likelihood of implantation.

Side Effects

Mayra may cause a range of adverse reactions. Most are mild and transient, but rare serious events can occur.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like.
  • Breast tenderness: swelling or discomfort.
  • Weight gain: modest increase in body weight.
  • Mood changes: irritability or mood swings.
  • Spotting: irregular light bleeding.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Arterial thrombosis: clot formation in arteries.
  • Hypertension: elevated blood pressure.
  • Liver disorders: jaundice or hepatic dysfunction.
  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Gallbladder disease: inflammation or stones.

Precautions & Warnings

Before prescribing Mayra, clinicians should evaluate patient history and risk factors.

  • Assess medical history: identify thrombosis, cardiovascular, or liver disease.
  • Avoid smoking: especially in women over 35 years of age.
  • Monitor blood pressure: hypertension may develop during therapy.
  • Review medication list: potential interactions can affect efficacy.
  • Consider liver function: contraindicated in severe hepatic impairment.
  • Store at ambient temperature: keep below 25°C, protect from moisture.

Avoid Interactions

Mayra can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Anticoagulants (warfarin): may reduce anticoagulant effect.
  • Antiepileptics (carbamazepine, phenytoin): increase hormone metabolism, lowering contraceptive efficacy.
  • Rifampicin and other strong enzyme inducers: may cause contraceptive failure.

Moderate Interactions (Monitor Closely)

  • Antibiotics (tetracycline, penicillins): may slightly reduce hormonal effect.
  • SSRIs (fluoxetine, sertraline): can increase hormone levels.
  • Herbal supplements (St. John's wort, ginseng): possible enzyme induction affecting efficacy.

Frequently Asked Questions

Mayra is prescribed as a combined hormonal contraceptive to prevent pregnancy and to help regulate menstrual cycles. It is indicated for women of reproductive age who require reliable birth control and for those seeking cycle control or relief from menstrual irregularities.

The ethinylestradiol component suppresses follicle‑stimulating hormone, while dienogest blocks the luteinizing hormone surge, together preventing ovulation. The formulation also thickens cervical mucus and alters the endometrial lining, creating conditions that are unfavorable for fertilisation and implantation.

The dosing regimen for Mayra is determined by the prescribing clinician based on individual health status and treatment goals. Typically, a standard combined oral contraceptive schedule is followed, but the exact number of tablets per cycle and any placebo days are set by the prescriber.

Mayra is contraindicated during pregnancy because it is intended to prevent conception. If pregnancy occurs, the product should be discontinued. While limited data exist for breastfeeding, combined oral contraceptives are generally used with caution; a healthcare professional should assess the risk‑benefit ratio for nursing mothers.

To request Mayra, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any special handling), and necessary import documentation.

Mayra contains the progestogen dienogest, which offers a slightly lower androgenic profile compared with some older progestins, potentially resulting in fewer acne‑related side effects. Its estrogen component, ethinylestradiol, is standard for combined pills, providing comparable contraceptive efficacy and cycle control to other products in the same class.

Mayra tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Mayra is taken orally, usually once daily at the same time each day. The tablets are swallowed with water and should be taken with or without food as directed by the prescriber. Consistent daily intake maximises contraceptive effectiveness.

The most serious risks include venous or arterial thromboembolism, hypertension, severe liver disease, and rare allergic reactions such as anaphylaxis. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should be closely monitored or may need alternative contraception.

Mayra is contraindicated in women with known or suspected pregnancy, active thromboembolic disease, uncontrolled hypertension, severe liver disease, or a history of estrogen‑dependent tumors. It should also be avoided by smokers over 35 years of age and by individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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