Product image of Mebeverine Teva (Mebeverine Hydrochloride) supplied by GNH India

Mebeverine Teva

Active Ingredient:
Mebeverine Hydrochloride
Origin:
EU

Mebeverine Teva (Mebeverine Hydrochloride)

Mebeverine, the active ingredient in Mebeverine Teva, is an antispasmodic presented as an oral tablet for oral use. It is employed to relieve abdominal cramps and discomfort associated with irritable bowel syndrome and other functional gastrointestinal disorders in adult patients. It works by relaxing smooth muscle in the gastrointestinal tract, helping to normalize bowel movements.

GNH India supplies Mebeverine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.

Manufacturer / TM Owner

Teva Uk Limited

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Indications & Clinical Uses

  • Mebeverine is used to treat functional gastrointestinal conditions by reducing smooth‑muscle spasms.
  • Irritable bowel syndrome: alleviates abdominal pain, cramping and irregular bowel habits associated with the condition.
  • Functional gastrointestinal disorders: reduces spasmodic episodes and improves patient comfort.
  • Spastic colon: diminishes colonic muscle contractions, helping to normalize transit.

How It Works

  • Mebeverine acts as a direct smooth‑muscle relaxant in the gastrointestinal tract, likely by inhibiting calcium influx into smooth‑muscle cells. This action reduces the intensity and frequency of intestinal spasms without affecting normal motility, thereby easing abdominal discomfort and irregular bowel movements.

Side Effects

Mebeverine may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dry mouth
  • Nausea
  • Headache
  • Dizziness
  • Abdominal discomfort
  • Constipation

Serious or Rare Side Effects

  • Allergic reactions (rash, itching, swelling)
  • Severe skin eruptions such as Stevens‑Johnson syndrome
  • Angioedema
  • Cardiac arrhythmia (rare)
  • Hepatic dysfunction (very rare)

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Assess renal and hepatic function: adjust use if significant impairment is present.
  • Monitor for allergic reactions: discontinue if rash, swelling or breathing difficulty occurs.
  • Avoid use in patients with known hypersensitivity to mebeverine or excipients.
  • Inform patients about possible dizziness: advise caution when driving or operating machinery.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Mebeverine may interact with other medicines; review patient medication lists.

Major Interactions (Avoid)

  • Strong anticholinergic agents: may increase antispasmodic effect and risk of constipation.
  • Monoamine oxidase inhibitors (MAOIs): potential for exaggerated gastrointestinal effects.

Moderate Interactions (Monitor Closely)

  • Other antispasmodic drugs: additive smooth‑muscle relaxation.
  • CYP450 substrates: mebeverine may alter metabolism of certain drugs.
  • Antidepressants (e.g., tricyclics): monitor for increased gastrointestinal side effects.

Frequently Asked Questions

Mebeverine Teva is prescribed to manage irritable bowel syndrome and other functional gastrointestinal disorders by reducing smooth‑muscle spasms that cause abdominal pain, cramping, and irregular bowel movements.

Mebeverine acts as a direct relaxant of gastrointestinal smooth muscle, likely by inhibiting calcium influx into muscle cells. This reduces the intensity of spasms without impairing normal gut motility.

The dosage of mebeverine is determined by the prescribing healthcare professional based on the patient’s condition, age, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for mebeverine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mebeverine is a direct smooth‑muscle relaxant that does not possess significant anticholinergic activity, which can make it better tolerated than some anticholinergic antispasmodics that often cause dry mouth and urinary retention.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep out of reach of children.

Mebeverine Teva is taken orally, usually with a glass of water. The exact timing (e.g., before meals) and frequency should follow the prescribing clinician’s directions.

Serious risks, though rare, include severe allergic reactions such as rash, swelling, angioedema, and rare skin conditions like Stevens‑Johnson syndrome. Any signs of hypersensitivity require immediate medical attention.

Patients with known hypersensitivity to mebeverine or any of its excipients should avoid the product. Caution is also advised for individuals with severe hepatic or renal impairment, and those taking strong anticholinergic or MAOI medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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