Meclodin (Clotrimazole, Metronidazole)

Clotrimazole inhibits the fungal enzyme lanosterol 14α‑demethylase, blocking ergosterol synthesis. Without ergosterol, the fungal cell membrane becomes permeable and dysfunctional, leading to cell death. This action targets Candida species responsible for vaginal yeast infections.

The dosing regimen for Meclodin is determined by the prescribing healthcare professional based on the specific infection, severity, and patient factors. The prescriber will provide detailed instructions on the amount to apply, frequency, and duration of therapy.

Safety data for Meclodin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To order Meclodin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Meclodin combines both clotrimazole and metronidazole in a single vaginal formulation, offering broader antimicrobial coverage than either agent alone. While clotrimazole targets fungal pathogens and metronidazole targets anaerobic bacteria and protozoa, the combination can treat mixed infections without the need for separate products.

Store Meclodin at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat. Ensure the container is tightly closed after each use to maintain product stability.

Meclodin is applied intravaginally. The prescribed amount is inserted into the vagina using the supplied applicator or a clean fingertip, typically once or twice daily as directed by the prescriber, and the treatment course is continued for the recommended number of days.

Serious risks include severe allergic reactions such as rash, swelling, or anaphylaxis, as well as rare but serious events like Stevens‑Johnson syndrome, severe vaginal ulceration, and hepatic dysfunction. Patients should seek immediate medical attention if they experience any of these symptoms.

Meclodin should be avoided by individuals with known hypersensitivity to clotrimazole, metronidazole, or any formulation excipients. It is also contraindicated in patients with severe liver impairment unless specifically advised by a physician, and it should be used with caution in pregnant or breastfeeding women after medical consultation.