Med-Angin (Benzydamine Hydrochloride)

Med-Angin, a topical NSAID, acts on inflammatory processes of the oral cavity and pharynx.

• Sore throat: relieves pain and reduces inflammation in the pharyngeal mucosa.
• Oral mucositis: eases discomfort and promotes healing of chemotherapy‑induced mucosal lesions.
• Stomatitis: diminishes irritation and swelling of the oral lining.
• Pharyngitis: provides symptomatic relief of throat inflammation.

• Benzydamine hydrochloride exerts its local effect by stabilising cell membranes and inhibiting the release of pro‑inflammatory cytokines such as IL‑1β and TNF‑α. This reduces vascular permeability and nociceptor activation in the oral and pharyngeal mucosa, resulting in anti‑inflammatory, analgesic and mild anesthetic actions without significant systemic absorption.

Adverse reactions are generally mild and confined to the site of application.

Common Side Effects

• Taste alteration: transient metallic or bitter taste.
• Local burning or stinging sensation.
• Mild oral irritation or erythema.
• Nausea or mild gastrointestinal discomfort.
• Dizziness or light‑headedness.

Serious or Rare Side Effects

• Allergic reactions: rash, pruritus, or angioedema.
• Severe oral ulceration or necrosis.
• Anaphylactic shock: rare but requires immediate medical attention.

Before using Med-Angin, consider the following safety measures.

• Pregnancy: safety not established; consult a healthcare professional before use.
• Breastfeeding: unknown safety profile; use only if benefit outweighs potential risk.
• Known hypersensitivity: avoid if you have a documented allergy to benzydamine or related compounds.
• Existing oral lesions: monitor for increased irritation or worsening of ulcers.
• Pediatric use: not recommended unless specifically prescribed by a clinician.
• Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Potential drug interactions should be reviewed with a healthcare provider.

Major Interactions (Avoid)

• Alcohol: may intensify local irritation and burning sensations.
• Concurrent topical anesthetics: risk of additive local anesthetic effect.

Moderate Interactions (Monitor Closely)

• Systemic NSAIDs: may increase overall anti‑inflammatory load.
• Corticosteroid mouth rinses: monitor for overlapping anti‑inflammatory actions.
• Anticoagulants: observe for any unexpected bleeding, although risk is low.