Medcovorin (Calcium Leucovorin Vials) 15mg

Medcovorin (Calcium Leucovorin) 15mg vials are used in supportive cancer care to reduce methotrexate toxicity and rescue normal cells. This folate analog supports healthy cell function during chemotherapy. Ideal for clinics and patients needing reliable rescue therapy. Short shelf life; store at ambient temperature.

Strength

15mg

Pack Size

Storage

Ambient

Manufacturer / TM Owner

Mediclone Health Care Pvt Ld

Select Quantity

Pack/s

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Indications & Clinical Uses

Calcium Leucovorin 15mg vials are commonly used to counteract the toxic effects of high-dose methotrexate chemotherapy, helping to protect healthy cells while allowing cancer treatment to proceed. It is also used in combination with 5-fluorouracil to enhance the effectiveness of certain chemotherapy regimens. Patients undergoing treatment for osteosarcoma, colorectal cancer, or acute lymphoblastic leukemia may receive this medication as part of their care plan. It supports folate-dependent cellular processes during intensive therapy.

Side Effects

Calcium Leucovorin works by replenishing folate levels in the body, which can become depleted during certain chemotherapy treatments. It helps restore normal cell function and supports recovery after methotrexate exposure. Patients may notice improved tolerance to chemotherapy when this rescue agent is used appropriately. The medication does not treat cancer directly but helps manage side effects of aggressive treatments.

Precautions & Warnings

Store Medcovorin vials at room temperature, away from moisture and direct light. Keep out of reach of children and pets. Inspect the vial for particles or discoloration before use; discard if any abnormalities are found. Always follow healthcare provider instructions for administration and timing. Avoid mixing with other medications unless directed by a medical professional.

Avoid Interactions

Calcium Leucovorin may interact with other folate antagonists or medications that affect folate metabolism, such as certain anticonvulsants or sulfonamides. Combining it with fluorouracil can enhance therapeutic effects but may also increase side effects. Alcohol and other substances that stress liver function should be used cautiously. Always inform your healthcare provider about all medications and supplements you are taking before starting treatment.

Frequently Asked Questions

It is primarily used to reduce toxic effects of high-dose methotrexate chemotherapy and to enhance the action of 5-fluorouracil in cancer treatment.

Store at room temperature, away from light and moisture. Do not freeze or refrigerate unless specified by instructions.

Use during pregnancy should only be considered if clearly needed and prescribed by a healthcare provider.

Yes, Calcium Leucovorin is a prescription medication and should only be used under medical supervision.

Side effects may include nausea, vomiting, or allergic reactions; report any unusual symptoms to a healthcare provider promptly.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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