Product image of Medilax (Lactulose) supplied by GNH India

Medilax

Active Ingredient:
Lactulose
Origin:
EU

Medilax (Lactulose)

Lactulose, the active ingredient in Medilax, is an osmotic laxative presented as an oral formulation for oral use. It is employed to relieve constipation and to manage hepatic encephalopathy by lowering intestinal ammonia levels in adult patients. It works by increasing osmotic pressure in the intestinal lumen, drawing water into the colon to facilitate bowel movements.

GNH India supplies Medilax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides reliable sourcing for healthcare providers across multiple regions.

Manufacturer / TM Owner

Viatris Aps

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lactulose is used to treat conditions related to bowel motility and ammonia accumulation.

  • Constipation: Relieves infrequent or difficult bowel movements by softening stools and increasing stool frequency.
  • Hepatic encephalopathy: Reduces blood ammonia levels, helping to prevent or treat episodes of neuropsychiatric disturbance in patients with liver disease.
  • Portal‑systemic encephalopathy: Supports long‑term control of neurocognitive symptoms in cirrhotic patients.

How It Works

  • Lactulose remains largely unabsorbed in the small intestine and reaches the colon where it is metabolized by bacterial flora into short‑chain fatty acids. This acidifies the colonic contents, increasing osmotic pressure and drawing water into the lumen, which softens stools and stimulates peristalsis. In hepatic encephalopathy, the acidic environment converts ammonia (NH3) to ammonium (NH4+), reducing its absorption and lowering systemic ammonia concentrations.

Side Effects

Lactulose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Flatulence: Excess gas production due to bacterial fermentation.
  • Abdominal cramping: Stomach discomfort from increased intestinal activity.
  • Diarrhea: Loose stools when the osmotic effect is pronounced.
  • Nausea: Mild queasiness after ingestion.
  • Bloating: Sensation of fullness in the abdomen.
  • Electrolyte imbalance: Minor changes in sodium or potassium levels.

Serious or Rare Side Effects

  • Severe dehydration: Excessive fluid loss requiring medical attention.
  • Marked electrolyte disturbances: Significant shifts in sodium, potassium, or calcium.
  • Allergic reaction: Rash, itching, or swelling indicating hypersensitivity.
  • Persistent abdominal pain: May signal an underlying gastrointestinal issue.

Precautions & Warnings

Before using Medilax, certain safety considerations should be observed.

  • Assess renal function: Adjust use in patients with impaired kidney function.
  • Monitor electrolytes: Watch for sodium and potassium changes during therapy.
  • Avoid abrupt dose increase: Titrate gradually to minimize gastrointestinal upset.
  • Use with caution in diabetics: Lactulose solutions contain sugars that may affect glucose control.
  • Pregnancy and lactation: Consult a healthcare professional before use.
  • Store at ambient temperature: Keep in the original container, protect from moisture and heat.

Avoid Interactions

Lactulose can interact with other medicines, requiring attention to avoid reduced efficacy or increased risk.

Major Interactions (Avoid)

  • Antibiotics (e.g., neomycin): May diminish lactulose's effect on ammonia reduction.
  • Magnesium‑containing laxatives: Heighten risk of electrolyte loss and diarrhea.
  • Loop or thiazide diuretics: Increase potential for dehydration and electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Antacids: May alter colonic pH and affect lactulose activity.
  • Probiotics: Could modify gut flora and influence drug metabolism.
  • Oral hypoglycemic agents: Monitor blood glucose as lactulose may affect carbohydrate absorption.

Frequently Asked Questions

Medilax contains lactulose, which is indicated for the relief of constipation and for the management of hepatic encephalopathy. In constipation, it softens stools and promotes regular bowel movements. In hepatic encephalopathy, it helps lower blood ammonia levels, reducing neuropsychiatric symptoms associated with liver disease.

Lactulose is an osmotic agent that reaches the colon unchanged, where intestinal bacteria ferment it into short‑chain fatty acids. This process acidifies the colonic environment, drawing water into the lumen to soften stools and stimulate peristalsis. The acidic pH also converts ammonia to ammonium, limiting its absorption and thereby decreasing systemic ammonia concentrations.

The dose of Medilax is individualized by the prescribing healthcare professional based on the patient’s condition, age, and response. Typical regimens start with a low dose that is gradually increased until the desired clinical effect is achieved, but exact amounts and frequency should only be set by a qualified prescriber.

Safety data for lactulose in pregnancy and lactation are limited. It is classified as a Category C medication in many regions, meaning risk cannot be ruled out. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential benefits and risks with their healthcare provider before using Medilax.

To request Medilax, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Medilax (lactulose) differs from polyethylene glycol‑based laxatives in that it is a disaccharide that is metabolized by colonic bacteria, providing both laxative and ammonia‑lowering effects. Polyethylene glycol acts purely as an osmotic agent without influencing ammonia levels. Choice of therapy depends on the clinical indication—lactulose is preferred when hepatic encephalopathy is a concern, whereas polyethylene glycol may be chosen for simple constipation without liver disease.

Medilax should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed when not in use. Do not freeze the product, and ensure it is kept out of reach of children.

Medilax is taken orally. The product is typically dissolved in a small amount of water or another suitable liquid before ingestion, although it can also be mixed with juice or milk to improve palatability. It should be taken as directed by the prescribing clinician, with or without food, according to the prescribed schedule.

Serious risks include severe dehydration, marked electrolyte disturbances (especially sodium and potassium), and rare allergic reactions such as rash, itching or swelling. Patients experiencing persistent diarrhea, abdominal pain, or signs of dehydration should seek medical attention promptly. Monitoring of fluid and electrolyte status is advisable during prolonged therapy.

Medilax is contraindicated in individuals with known hypersensitivity to lactulose or any of its excipients. It should be used with caution in patients with severe renal impairment, uncontrolled diabetes, or active gastrointestinal obstruction. Children, pregnant or breastfeeding women should only use it after a thorough risk‑benefit assessment by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.