Product image of Medipyrin (Paracetamol) supplied by GNH India

Medipyrin

Active Ingredient:
Paracetamol
Origin:
EU

Medipyrin (Paracetamol)

Paracetamol, the active ingredient in Medipyrin, is a Analgesic; Antipyretic presented as a tablet for oral use. It relieves fever, headache, musculoskeletal pain, toothache and other cold‑related symptoms in adults and children when appropriate dosing is generally safely under medical guidance. It is formulated to meet EU quality standards and is widely available in retail pharmacies.

GNH India supplies Medipyrin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks across Europe, Asia and Africa.

Manufacturer / TM Owner

Glenmark Pharmaceuticals S.R.O.

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Indications & Clinical Uses

  • Paracetamol acts centrally to reduce fever and alleviate pain, making it suitable for several common conditions.
  • Fever: lowers body temperature and provides comfort.
  • Headache: eases tension and migraine‑related pain.
  • Musculoskeletal pain: reduces aches associated with strains, sprains and arthritis.
  • Toothache: diminishes dental pain and inflammation.
  • Cold symptoms: helps relieve mild fever and headache accompanying upper‑respiratory infections.

How It Works

  • Paracetamol inhibits central cyclooxygenase (COX) enzymes, primarily COX‑2, leading to reduced synthesis of prostaglandins in the brain and spinal cord. This decrease in prostaglandin levels diminishes the perception of pain and lowers the hypothalamic set‑point for temperature regulation, thereby providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Abdominal discomfort: transient stomach pain.
  • Headache: occasional worsening of existing headache.
  • Skin rash: mild itching or erythema.
  • Dizziness: brief light‑headedness.
  • Elevated liver enzymes: mild, reversible changes.

Serious or Rare Side Effects

  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Acute liver failure: especially with overdose or chronic high intake.
  • Blood disorders: agranulocytosis or thrombocytopenia.
  • Anaphylaxis: rare severe allergic response.

Precautions & Warnings

  • When using Medipyrin, certain precautions help minimize risk and ensure safe use.
  • Liver function monitoring: avoid use in patients with severe hepatic impairment.
  • Alcohol consumption: limit alcohol to reduce liver stress.
  • Maximum daily dose: do not exceed the recommended total paracetamol amount from all sources.
  • Use in children: follow pediatric dosing guidelines and avoid use in infants under 2 months.
  • Concomitant paracetamol products: avoid simultaneous use of other paracetamol‑containing medicines.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Paracetamol may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Carbamazepine: reduced analgesic effect.
  • Isoniazid: heightened hepatotoxic potential.
  • Alcohol: additive liver toxicity.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: possible reduction in contraceptive effectiveness.
  • Phenytoin: altered plasma levels of both drugs.
  • HIV protease inhibitors: may increase paracetamol plasma concentrations.

Frequently Asked Questions

Medipyrin contains paracetamol and is used to relieve mild to moderate pain such as headache, toothache, musculoskeletal discomfort, and to reduce fever associated with colds or other infections. It is an over‑the‑counter option for adults and children when dosing is appropriate.

Paracetamol works by inhibiting central cyclooxygenase enzymes, which reduces the production of prostaglandins in the brain and spinal cord. This action lowers the body’s temperature set‑point and diminishes the perception of pain, providing both antipyretic and analgesic effects.

The exact dose of Medipyrin is determined by a healthcare professional based on the patient’s age, weight, and clinical condition. The prescriber will set the appropriate amount and frequency, and patients should follow that guidance without exceeding the recommended total daily limit.

Safety data for paracetamol in pregnancy and lactation are limited, and use should only be considered when clearly needed. Women who are pregnant or breastfeeding should consult their physician before taking Medipyrin to weigh potential benefits against any risks.

To order Medipyrin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both Medipyrin (paracetamol) and ibuprofen relieve pain and fever, but ibuprofen also has anti‑inflammatory properties. Paracetamol is generally gentler on the stomach and does not affect platelet function, whereas ibuprofen may cause gastrointestinal irritation and should be avoided in certain cardiovascular conditions.

Medipyrin tablets should be stored at room temperature, below 25 °C, in their original packaging to protect them from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Medipyrin is taken orally with a glass of water. It can be taken with or without food, but if stomach upset occurs, it may be helpful to take the tablet after a meal. The exact administration schedule should follow the prescribing clinician’s instructions.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome, acute liver failure especially after overdose, and rare blood disorders. Prompt medical attention is required if signs of rash, jaundice, unexplained bruising or severe fatigue develop while using the product.

Medipyrin should be avoided by individuals with known hypersensitivity to paracetamol, those with severe liver disease, and patients who are already taking the maximum daily amount of paracetamol from other sources. Children under two months of age should not receive this medication without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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