Product image of Mediveine (Diosmin) supplied by GNH India

Mediveine

Active Ingredient:
Diosmin
Origin:
EU

Mediveine (Diosmin)

Diosmin, the active ingredient in Mediveine, is a flavonoid presented as an oral dosage form for oral use. It is commonly employed to support vascular health and manage chronic venous conditions in adults.
GNH India supplies Mediveine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Des Realisations Therapeutiques Elerte

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Diosmin is used primarily in disorders of the venous and vascular system.

  • Chronic venous insufficiency: improves venous tone and reduces leg swelling and pain.
  • Hemorrhoidal disease: lessens bleeding, discomfort and inflammation of hemorrhoids.
  • Lymphatic edema: supports lymphatic drainage and decreases fluid accumulation in affected limbs.

How It Works

  • Diosmin is metabolized to diosmetin, which enhances venous wall contractility, reduces capillary permeability, and exhibits anti‑inflammatory and antioxidant activity. These actions collectively improve venous return, lower venous pressure, and protect microvascular integrity, contributing to symptom relief in venous disorders.

Side Effects

Adverse reactions reported with oral diosmin are generally mild to moderate.

Common Side Effects

  • Gastrointestinal discomfort: nausea, abdominal pain or dyspepsia.
  • Headache.
  • Dizziness.
  • Skin rash or pruritus.
  • Mild flushing.
  • Diarrhoea.

Serious or Rare Side Effects

  • Allergic reactions: urticaria, angioedema.
  • Anaphylaxis.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Hepatic dysfunction: elevated liver enzymes.
  • Thrombocytopenia.
  • Severe hypersensitivity with systemic involvement.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal and hepatic function: adjust use if impairment is present.
  • Monitor for hypersensitivity: discontinue if allergic signs appear.
  • Caution in pregnancy and breastfeeding: use only if clearly needed.
  • Review concomitant anticoagulant or antiplatelet therapy: increased bleeding risk.
  • Store at room temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Diosmin may alter the effect of several medications.

Major Interactions (Avoid)

  • Warfarin or other vitamin K antagonists: enhanced anticoagulant effect.
  • Aspirin and clopidogrel: additive antiplatelet activity increasing bleeding risk.
  • Other flavonoid supplements: potential for synergistic adverse effects.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): monitor for gastrointestinal irritation.
  • Antihypertensive agents: possible additive blood pressure lowering.
  • Oral contraceptives: observe for altered hormonal efficacy.

Frequently Asked Questions

Mediveine contains diosmin, a flavonoid that is primarily used to support vascular health. It is indicated for chronic venous insufficiency, hemorrhoidal disease, and lymphatic edema, helping to reduce swelling, pain, and inflammation associated with these conditions.

Diosmin is converted to diosmetin after oral absorption. The metabolite strengthens venous wall contractility, lowers capillary permeability, and provides anti‑inflammatory and antioxidant effects. These actions improve venous return and reduce fluid buildup in the affected tissues.

The appropriate dose of Mediveine is determined by the prescribing healthcare professional based on the individual’s condition, severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for diosmin in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with synthetic venotonic drugs, diosmin is a natural flavonoid with a well‑documented safety profile. It offers similar efficacy in reducing venous symptoms but may have fewer systemic side effects. Clinical choice depends on patient tolerance, comorbidities, and physician preference.

Mediveine should be stored at room temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability.

Mediveine is taken orally, usually with water. The tablet (or other oral form) should be swallowed whole and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, Stevens‑Johnson syndrome, hepatic dysfunction, and significant thrombocytopenia. Patients should seek immediate medical attention if they experience signs of a severe reaction.

Mediveine is contraindicated in individuals with known hypersensitivity to diosmin or any other flavonoid components. Patients on anticoagulant therapy, those with severe liver disease, or those who have experienced serious allergic reactions to similar agents should avoid its use unless advised otherwise by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.