Product image of Medovert (Cinnarizine, Dimenhydrinate) supplied by GNH India

Medovert

Active Ingredient:
Cinnarizine, Dimenhydrinate
Origin:
EU

Medovert (Cinnarizine, Dimenhydrinate)

Cinnarizine and Dimenhydrinate, the active ingredients in Medovert, are antihistamines presented as an oral tablet for oral use. They are employed to alleviate motion‑related nausea, vertigo and other vestibular disturbances in adults and children as directed by a healthcare professional.

GNH India supplies Medovert as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medochemie Ltd.

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Indications & Clinical Uses

  • Medovert, containing cinnarizine and dimenhydrinate, is used to manage vestibular and histamine‑mediated conditions.
  • Motion sickness: reduces nausea and vomiting associated with travel.
  • Vertigo: alleviates dizziness caused by vestibular dysfunction.
  • Nausea: controls nausea from various causes.
  • Vomiting: helps suppress vomiting episodes.

How It Works

  • Cinnarizine blocks calcium channels in the vestibular apparatus, decreasing vestibular excitability, while dimenhydrinate antagonizes peripheral and central H1 histamine receptors. The combined actions reduce the neural signals that trigger nausea, vomiting and vertigo, providing symptomatic relief in motion‑related and vestibular disorders.

Side Effects

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivation leading to a parched sensation.
  • Headache: mild to moderate head pain.
  • Gastrointestinal discomfort: nausea, abdominal pain or mild diarrhea.

Serious or Rare Side Effects

  • Extrapyramidal symptoms: involuntary muscle movements or tremor.
  • Severe allergic reactions: rash, swelling, or difficulty breathing.
  • Hepatic dysfunction: signs of liver injury such as jaundice.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Blood dyscrasias: abnormal blood counts.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • Before using Medovert, consider the following precautions.
  • Pregnancy: consult a healthcare provider before use.
  • Elderly: monitor for increased sedation and falls.
  • Driving: avoid operating machinery until individual response is known.
  • Medical conditions: use cautiously in hepatic or renal impairment.
  • Drug interactions: review all concomitant medications.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Medovert may interact with several medicines; review the following categories.

Major Interactions (Avoid)

  • Alcohol: additive sedation and impaired coordination.
  • CNS depressants: increased drowsiness and respiratory depression.
  • Anticholinergic drugs: heightened anticholinergic effects such as dry mouth and blurred vision.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible additive hypotensive effect.
  • Antidepressants (SSRIs): monitor for serotonin syndrome symptoms.
  • Other antihistamines: increased anticholinergic load and sedation.

Frequently Asked Questions

Medovert is an oral combination of cinnarizine and dimenhydrinate indicated for the prevention and treatment of motion‑related nausea, vomiting, vertigo and other vestibular disturbances. It is commonly prescribed for travelers, patients with inner‑ear disorders and individuals experiencing nausea from various causes.

Cinnarizine blocks calcium channels in the vestibular system, reducing excitability that contributes to dizziness. Dimenhydrinate antagonizes peripheral and central H1 histamine receptors, diminishing the histamine‑mediated signals that trigger nausea and vomiting. Together they provide complementary anti‑vertigo and anti‑emetic effects.

The dosage of Medovert is individualized by the prescribing clinician based on the patient’s age, condition severity and response to therapy. Healthcare professionals determine the appropriate strength, frequency and duration of treatment, and patients should follow the prescribed regimen exactly.

Safety data for cinnarizine and dimenhydrinate in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy or breastfeeding should discuss alternatives with their healthcare provider.

To order Medovert, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Medovert combines a calcium‑channel blocker (cinnarizine) with an H1‑antihistamine (dimenhydrinate), offering both vestibular stabilization and antihistamine effects. Compared with single‑agent drugs such as meclizine, Medovert may provide broader symptom control for vertigo and motion sickness, though individual response and tolerability vary.

Store Medovert at ambient temperature, preferably below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Medovert is taken orally, usually with a glass of water. It can be taken with or without food, unless the prescribing clinician advises otherwise. Swallow the tablet whole; do not crush or chew unless instructed by a healthcare professional.

Serious adverse reactions, although rare, include extrapyramidal symptoms such as involuntary muscle movements, severe allergic responses (e.g., anaphylaxis, skin rash), hepatic dysfunction, cardiac arrhythmias, and blood‑cell abnormalities. Patients should seek immediate medical attention if they experience any of these symptoms.

Medovert is contraindicated in individuals with known hypersensitivity to cinnarizine, dimenhydrinate or any excipients in the formulation. It should be avoided in patients with severe hepatic impairment, uncontrolled epilepsy, or those taking medications that may cause dangerous additive sedation or anticholinergic effects without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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