Product image of Medovir (Aciclovir) supplied by GNH India

Medovir

Active Ingredient:
Aciclovir
Origin:
EU

Medovir (Aciclovir)

Aciclovir, the active ingredient in Medovir, is an antiviral presented as a topical preparation for external use. It is used to treat herpes simplex virus infections of the skin and lips, helping to reduce lesion duration and discomfort in affected individuals.

GNH India supplies Medovir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable sourcing for bulk and retail needs. Its distribution network ensures timely delivery across multiple continents, supporting healthcare providers in managing viral skin conditions.

Manufacturer / TM Owner

Medochemie Ltd.

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Indications & Clinical Uses

Aciclovir is an antiviral agent that targets herpes simplex virus infections of the skin and mucous membranes.

  • Herpes labialis: shortens lesion duration and alleviates pain.
  • Herpes simplex skin infections: limits lesion spread and promotes faster resolution.
  • Herpes zoster skin lesions: reduces local symptoms when applied early.

How It Works

  • Aciclovir is phosphorylated by viral thymidine kinase to aciclovir monophosphate, which is then converted to the active triphosphate form by cellular kinases. The triphosphate competitively inhibits viral DNA polymerase, terminating DNA chain elongation and preventing replication of herpes simplex virus DNA within infected cells.

Side Effects

Aciclovir topical is generally well tolerated, but local reactions may occur.

Common Side Effects

  • Mild skin irritation at the application site.
  • Burning or stinging sensation.
  • Itching or redness.
  • Dryness or flaking of the skin.

Serious or Rare Side Effects

  • Allergic contact dermatitis with swelling or rash.
  • Severe skin reaction such as Stevens‑Johnson syndrome.
  • Eye irritation if applied near the eye.
  • Systemic toxicity (rare) with signs of renal impairment.

Precautions & Warnings

When using Medovir, consider the following precautions.

  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: unknown safety; weigh potential benefits against risks.
  • Age: not recommended for children under 12 years without medical advice.
  • Application site: avoid contact with eyes, mucous membranes, and broken skin.
  • Allergy: discontinue use and seek medical attention if a severe skin reaction develops.
  • Store at below 25°C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Aciclovir topical may interact with other agents applied to the same skin area.

Major Interactions (Avoid)

  • Probenecid: can increase systemic aciclovir levels if significant absorption occurs.
  • Nephrotoxic drugs: caution when used concurrently due to potential systemic exposure.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask local irritation and delay detection of adverse reactions.
  • Other antiviral creams: concurrent use may reduce overall efficacy.
  • Alcohol‑based hand sanitizers: can increase skin irritation when used together.

Frequently Asked Questions

Medovir is a topical formulation containing aciclovir that is used to treat external herpes simplex virus infections, such as cold sores (herpes labialis) and other skin lesions caused by the virus. It helps to reduce the duration of lesions, relieve pain, and limit viral spread on the skin.

Aciclovir is converted inside infected cells to its active triphosphate form. This metabolite competitively inhibits the viral DNA polymerase enzyme, preventing the synthesis of viral DNA and thereby halting replication of the herpes simplex virus. The result is a reduction in viral replication at the site of application.

The dosage regimen for Medovir is determined by the prescribing healthcare professional based on the specific indication, severity of the infection, and patient factors. The prescriber will provide instructions on how often to apply the cream and for how many days.

Safety data for topical aciclovir in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Medovir.

To order Medovir, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. The team then replies with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The most common alternative topical antiviral is penciclovir cream. Both aciclovir (Medovir) and penciclovir inhibit viral DNA synthesis, but aciclovir has a longer history of use and is available over‑the‑counter in many regions. Clinical studies suggest comparable efficacy, while individual response may vary.

Medovir should be stored at temperatures below 25 °C, in its original container, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.

Apply a thin layer of Medovir to the affected skin area, typically five times daily, or as directed by a healthcare professional. Wash hands before and after application, avoid contact with eyes, and do not cover the treated area with airtight dressings unless advised.

While rare, serious adverse reactions can include severe allergic dermatitis, Stevens‑Johnson syndrome, or ocular irritation if the product contacts the eye. Users should discontinue the cream and seek immediate medical attention if they experience extensive rash, swelling, blistering, or visual disturbances.

Medovir should not be used by individuals with a known hypersensitivity to aciclovir or any of the excipients in the formulation. It is also contraindicated on mucous membranes, in the eyes, or on severely damaged skin without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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