Product image of Mefenamic Acid Chemidex Pharma (Mefenamic Acid) supplied by GNH India

Mefenamic Acid Chemidex Pharma

Active Ingredient:
Mefenamic Acid
Origin:
EU

Mefenamic Acid Chemidex Pharma (Mefenamic Acid)

Mefenamic Acid, the active ingredient in Mefenamic Acid Chemidex Pharma, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, dysmenorrhea and various inflammatory conditions in adults.
GNH India supplies Mefenamic Acid Chemidex Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chemidex Pharma Limited

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Indications & Clinical Uses

  • Mefenamic Acid acts as an NSAID to reduce pain and inflammation in several common conditions.
  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches.
  • Dysmenorrhea: alleviates menstrual cramps and associated discomfort.
  • Inflammatory conditions: reduces swelling and pain in conditions such as osteoarthritis and rheumatoid arthritis.

How It Works

  • Mefenamic Acid non‑selectively inhibits cyclooxygenase enzymes COX‑1 and COX‑2, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to lowered inflammation, pain signaling, and fever responses at the site of tissue injury.

Side Effects

Mefenamic Acid may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea or upset stomach
  • Dyspepsia or heartburn
  • Headache
  • Dizziness
  • Mild rash or itching
  • Diarrhoea

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Acute renal impairment
  • Hepatic dysfunction or jaundice
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Anaphylactic or anaphylactoid reactions
  • Blood dyscrasias including agranulocytosis

Precautions & Warnings

Before prescribing Mefenamic Acid, clinicians should consider several safety factors.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Monitor renal function: use caution in patients with impaired kidney function.
  • Use lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Pregnancy and breastfeeding: safety not established; weigh benefits against potential risks.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Mefenamic Acid can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Lithium: may raise lithium serum levels.
  • Methotrexate: enhanced toxicity.
  • Other NSAIDs or aspirin: heightened gastrointestinal and renal adverse effects.
  • ACE inhibitors: potential reduction in renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics: may exacerbate renal impairment.
  • Corticosteroids: increased risk of GI ulceration.
  • SSRIs or SNRIs: additive bleeding risk.
  • Antihypertensives: possible reduction in blood pressure control.
  • Oral hypoglycemics: may affect glucose control.

Frequently Asked Questions

Mefenamic Acid Chemidex Pharma is prescribed to manage mild to moderate pain, menstrual cramps (dysmenorrhea), and inflammatory disorders such as osteoarthritis or rheumatoid arthritis. It works by reducing inflammation and pain signals, providing symptomatic relief in these common conditions.

Mefenamic acid inhibits both COX‑1 and COX‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, the drug diminishes inflammation, pain perception, and fever responses at the site of tissue injury.

The specific dose of Mefenamic Acid Chemidex Pharma is determined by the prescribing clinician based on the patient’s condition, age, weight, and response to therapy. Only a qualified health professional should set the dosage regimen.

Safety data for mefenamic acid in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mefenamic acid belongs to the anthranilic acid class of NSAIDs and offers analgesic and anti‑inflammatory effects similar to ibuprofen or naproxen. Its potency for dysmenorrhea is often highlighted, but like other NSAIDs, it shares comparable gastrointestinal and renal safety considerations.

Mefenamic Acid Chemidex Pharma should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, heat and direct sunlight to maintain stability.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with meals may reduce stomach irritation. Patients should follow the prescribing clinician’s instructions for timing and frequency.

Serious adverse events include gastrointestinal bleeding or ulceration, severe renal impairment, hepatic injury, life‑threatening skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Prompt medical attention is required if any of these symptoms develop.

Mefenamic acid is contraindicated in individuals with known hypersensitivity to the drug or other NSAIDs, active gastrointestinal ulcers, severe renal or hepatic disease, and in patients who have experienced previous serious skin reactions to NSAIDs. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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