Product image of Mefenamic Acid Strides Pharma Uk (Mefenamic Acid) supplied by GNH India

Mefenamic Acid Strides Pharma Uk

Active Ingredient:
Mefenamic Acid
Origin:
EU

Mefenamic Acid Strides Pharma Uk (Mefenamic Acid)

Mefenamic acid, the active ingredient in Mefenamic Acid Strides Pharma, is a NSAID (fenamate) presented as a oral tablet for systemic use. It treats mild to moderate pain, menstrual pain and inflammatory conditions such as arthritis. The drug belongs to the fenamate subclass of non‑steroidal anti‑inflammatory agents and works by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis and associated discomfort. It is commonly prescribed for short‑term management of acute pain episodes and is available only by prescription in most jurisdictions.

GNH India supplies Mefenamic Acid Strides Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Strides Pharma Uk Limited

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Indications & Clinical Uses

Mefenamic acid is an NSAID that reduces inflammation and pain by targeting the cyclooxygenase pathway.

  • Mild to moderate pain: provides analgesic relief for acute pain such as dental or musculoskeletal discomfort.
  • Dysmenorrhea: alleviates menstrual cramps and associated pelvic pain.
  • Arthritis: reduces inflammation and pain in osteoarthritis or rheumatoid arthritis flares.

How It Works

  • Mefenamic acid inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever responses, accounting for its analgesic and anti‑inflammatory properties.

Side Effects

Mefenamic acid may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: life‑threatening allergic response.
  • Blood dyscrasias: agranulocytosis or aplastic anemia.

Precautions & Warnings

Before prescribing mefenamic acid, clinicians should consider several safety measures.

  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor hepatic function: avoid in severe liver disease.
  • Avoid in third trimester pregnancy: risk to the fetus.
  • Use caution with concurrent NSAIDs or anticoagulants: increased bleeding risk.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Mefenamic acid can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened hemorrhage risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: may reduce renal function.
  • Lithium: NSAIDs can increase lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Mefenamic Acid Strides Pharma contains mefenamic acid, an NSAID indicated for the relief of mild to moderate pain, menstrual cramps (dysmenorrhea), and inflammatory conditions such as osteoarthritis or rheumatoid arthritis. It is prescribed for short‑term management of acute pain episodes and is available only by prescription.

Mefenamic acid works by inhibiting cyclooxygenase enzymes (COX‑1 and COX‑2), which reduces the synthesis of prostaglandins—key mediators of inflammation, pain, and fever. Lower prostaglandin levels diminish the inflammatory response and decrease pain signaling throughout the body.

The appropriate dose of mefenamic acid is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health status. Dosage regimens are individualized, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

Mefenamic acid is classified as Pregnancy Category C, meaning risk cannot be ruled out and it should be avoided unless the potential benefit justifies the potential risk to the fetus. It is also excreted in breast milk, so breastfeeding mothers should consult their physician before using this medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details, and any necessary import documentation.

Both mefenamic acid and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Mefenamic acid is a fenamate, often considered slightly more potent for dysmenorrhea, while ibuprofen has a broader safety profile for long‑term use. Choice between them depends on the specific clinical scenario, patient tolerance, and physician preference.

Store the product at ambient temperature below 25 °C. Keep it in the original packaging to protect it from moisture and light. Do not store in a humid bathroom cabinet or near heat sources, and keep out of reach of children.

Mefenamic Acid Strides Pharma is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce gastrointestinal discomfort. Patients should swallow tablets whole and not crush or chew them unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, renal impairment, hepatic dysfunction, and anaphylactic reactions. Patients should seek immediate medical attention if they notice signs of bleeding, rash, swelling, or sudden kidney or liver problems.

Mefenamic acid should be avoided in patients with known hypersensitivity to fenamates or other NSAIDs, those with active peptic ulcer disease, severe heart, liver, or kidney failure, and in the third trimester of pregnancy. Caution is also advised for individuals on anticoagulants, other NSAIDs, or with a history of asthma triggered by aspirin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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