Product image of Megalac (Hydrotalcite) supplied by GNH India

Megalac

Active Ingredient:
Hydrotalcite
Origin:
EU

Megalac (Hydrotalcite)

Hydrotalcite, the active ingredient in Megalac, is an antacid presented as an oral dosage form for oral use. It neutralizes excess gastric acid and is indicated for relief of heartburn, acid indigestion, gastric ulcer and gastro‑oesophageal reflux disease in adults and adolescents.

GNH India supplies Megalac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krewel Meuselbach Gmbh

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Indications & Clinical Uses

Megalac is an antacid that acts on excess gastric acidity to relieve symptoms of several upper‑digestive conditions.

  • Heartburn: provides rapid relief of burning sensation by neutralising excess stomach acid.
  • Acid indigestion: reduces discomfort and bloating associated with hyperacidity.
  • Gastric ulcer: promotes ulcer healing by decreasing acid exposure to the mucosa.
  • Gastro‑oesophageal reflux disease: alleviates reflux symptoms through acid neutralisation.

How It Works

  • Hydrotalcite works by releasing magnesium and aluminum hydroxide ions when it contacts gastric fluid. These hydroxides neutralise hydrogen ions, raising gastric pH. In addition, the compound forms a protective coating on the gastric mucosa, limiting further irritation and allowing the mucosal lining to recover.

Side Effects

Megalac may cause unwanted reactions, most of which are mild and transient.

Common Side Effects

  • Mild constipation or loose stools.
  • Temporary metallic taste in the mouth.
  • Mild abdominal discomfort or bloating.
  • Nausea.
  • Dry mouth.

Serious or Rare Side Effects

  • Hypermagnesemia in patients with severe renal impairment.
  • Severe allergic reactions such as rash, itching, swelling or difficulty breathing.
  • Electrolyte imbalance leading to muscle weakness or irregular heartbeat.

Precautions & Warnings

Before using Megalac, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Renal impairment: use with caution and under medical supervision.
  • Concomitant medications: review all current drugs for potential interactions.
  • Elderly patients: dosage may need adjustment due to altered metabolism.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Megalac can affect the absorption or action of several medicines.

Major Interactions (Avoid)

  • Tetracycline antibiotics: reduced absorption and effectiveness.
  • Iron supplements: decreased antacid efficacy and iron uptake.
  • Fluoroquinolone antibiotics: impaired absorption.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of anticoagulant effect.
  • Digoxin: monitor serum levels for potential changes.
  • Beta‑blockers: may require dose adjustment.

Frequently Asked Questions

Megalac is an over‑the‑counter antacid containing hydrotalcite. It is used to relieve symptoms of heartburn, acid indigestion, gastric ulcer and gastro‑oesophageal reflux disease by neutralising excess stomach acid.

Hydrotalcite releases magnesium and aluminum hydroxide when it contacts gastric fluid. These hydroxides neutralise hydrogen ions, raising the pH of stomach contents, and create a protective coating on the mucosa that reduces irritation.

The appropriate dose of Megalac is determined by the prescribing healthcare professional based on the individual’s condition, age and response. Patients should follow the prescriber’s instructions and the product label.

Pregnant or breastfeeding individuals should consult their healthcare provider before using Megalac. While antacids are generally considered low risk, professional guidance ensures safety for both mother and child.

To order Megalac, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Megalac’s hydrotalcite provides both acid neutralisation and a mucosal protective layer, unlike some antacids that only raise pH. This dual action can be advantageous for patients needing rapid symptom relief and mucosal protection, such as those with gastric ulcers.

Store Megalac at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Megalac is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their prescriber or the product label.

Serious risks include hypermagnesemia in patients with severe renal dysfunction and rare allergic reactions such as rash, swelling or breathing difficulties. Any signs of these conditions require immediate medical attention.

Individuals with known hypersensitivity to hydrotalcite, magnesium or aluminum compounds should avoid Megalac. Patients with severe renal impairment should use it only under medical supervision, and it is not recommended for children unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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