Product image of Meglucon (Metformin Hydrochloride) supplied by GNH India

Meglucon

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Meglucon (Metformin Hydrochloride)

Metformin Hydrochloride, the active ingredient in Meglucon, is a biguanide presented as an oral tablet for oral use. It is used to improve blood glucose control in adults with type 2 diabetes mellitus.

GNH India supplies Meglucon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz D.O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Meglucon (metformin) is employed in the management of disorders related to impaired glucose regulation.

  • Type 2 diabetes mellitus: lowers fasting and post‑prandial blood glucose levels.
  • Prediabetes: reduces the risk of progression to overt diabetes.
  • Polycystic ovary syndrome: helps restore regular ovulatory cycles and improves insulin resistance.

How It Works

  • Metformin Hydrochloride acts primarily by inhibiting hepatic gluconeogenesis, thereby decreasing hepatic glucose output. It also reduces intestinal glucose absorption and enhances peripheral insulin sensitivity, leading to increased glucose uptake by muscle and adipose tissue without stimulating insulin secretion.

Side Effects

Metformin is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Diarrhea: frequent loose stools, especially during treatment initiation.
  • Abdominal discomfort: cramping or bloating.
  • Metallic taste: transient alteration in taste perception.
  • Weight loss: modest reduction in body weight.
  • Vitamin B12 deficiency: decreased absorption with long‑term use.

Serious or Rare Side Effects

  • Lactic acidosis: life‑threatening accumulation of lactate, especially in renal impairment.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Hypoglycemia: uncommon when used alone but possible with concomitant insulin or sulfonylureas.

Precautions & Warnings

Before initiating Meglucon, several safety considerations should be observed.

  • Renal function assessment: avoid use in severe renal impairment.
  • Hepatic function monitoring: contraindicated in active liver disease.
  • Lactic acidosis risk: discontinue before any radiographic contrast studies.
  • Elderly patients: start at lower dose and monitor tolerance.
  • Concomitant medications: review for drugs that may affect renal clearance.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Metformin may interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Iodinated contrast agents: increase risk of acute kidney injury and lactic acidosis.
  • Alcohol: potentiates lactic acidosis, especially with chronic intake.
  • Cimetidine: may raise metformin plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: can mask hypoglycemia symptoms.
  • Diuretics and ACE inhibitors: may affect renal function and metformin clearance.
  • NSAIDs: can reduce renal perfusion, increasing metformin exposure.

Frequently Asked Questions

Meglucon contains metformin hydrochloride and is used to improve blood glucose control in adults with type 2 diabetes mellitus. It may also be prescribed for prediabetes and polycystic ovary syndrome to address insulin resistance.

Metformin reduces the liver’s production of glucose, decreases the amount of glucose absorbed from the intestine, and enhances the sensitivity of muscle and fat cells to insulin, which together lower blood sugar levels without increasing insulin secretion.

The dose of Meglucon is individualized by the prescribing clinician based on the patient’s clinical condition, renal function, and response to therapy. The prescriber determines the appropriate strength, frequency, and titration schedule.

Meglucon is classified as Pregnancy Category B, indicating no evidence of risk in animal studies and a lack of well‑controlled studies in pregnant women. It may be used if the potential benefit justifies the potential risk. Breastfeeding mothers should consult their physician, as metformin does pass into breast milk in small amounts.

To place an order, submit an enquiry on the Meglucon product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Meglucon (metformin) belongs to the biguanide class and is often first‑line therapy because it improves insulin sensitivity without causing weight gain. Compared with sulfonylureas, it carries a lower risk of hypoglycemia, and unlike insulin, it is administered orally. It is frequently combined with other agents when monotherapy does not achieve target glucose levels.

Meglucon tablets should be stored at ambient temperature, below 25 °C, in the original blister pack or container to protect them from moisture and light. Keep the medication out of reach of children and do not use after the expiry date.

Meglucon is taken orally, usually with meals to reduce gastrointestinal discomfort. The tablets should be swallowed whole with a full glass of water. Patients should follow the dosing schedule prescribed by their healthcare provider.

The most serious risk is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, dehydration, or excessive alcohol intake. Prompt medical attention is required if symptoms such as rapid breathing, muscle pain, or abdominal discomfort develop.

Meglucon is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and in those with known hypersensitivity to metformin or any component of the formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.