Product image of Mekostest 36 (Bacitracin, Hydrocortisone Butyrate, Tixocortol Pivalate, Bronopol, Budesonide, Chlorquinaldol, Clio) supplied by GNH India

Mekostest 36

Active Ingredient:
Bacitracin, Hydrocortisone Butyrate, Tixocortol Pivalate, Bronopol, Budesonide, Chlorquinaldol, Clio
Origin:
EU

Mekostest 36 (Bacitracin, Hydrocortisone Butyrate, Tixocortol Pivalate, Bronopol, Budesonide, Chlorquinaldol, Clio)

Bacitracin, the active ingredient in Mekostest 36, is a dermatological antimicrobial presented as a topical formulation for skin use. It is employed to treat bacterial skin infections and inflammatory dermatoses in both adults and children. The combination formulation also includes anti‑inflammatory corticosteroids and antiseptic agents that broaden its therapeutic scope.

GNH India supplies Mekostest 36 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements across EU and global markets.

Manufacturer / TM Owner

Smartpractice Denmark Aps

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Indications & Clinical Uses

Mekostest 36 is a topical combination used in dermatology to manage bacterial, inflammatory and fungal skin conditions.

  • Impetigo: reduces bacterial colonisation and promotes lesion healing.
  • Atopic dermatitis flare: decreases inflammation, redness and itching.
  • Contact dermatitis: alleviates inflammatory response and prevents secondary infection.
  • Superficial fungal infection: provides antifungal activity to clear mild dermatophyte lesions.
  • Seborrheic dermatitis: controls microbial overgrowth and reduces scaling.
  • Minor burns: soothes irritation and helps prevent infection.

How It Works

  • Mekostest 36 combines several agents that act at different biological targets. Bacitracin interferes with bacterial cell‑wall synthesis, while hydrocortisone butyrate, tixocortol pivalate and budesonide bind glucocorticoid receptors to suppress cytokine release and reduce inflammation. Bronopol and chlorquinaldol provide broad‑spectrum antiseptic activity, and clio (clioquinol) chelates metal ions to inhibit fungal growth. The synergistic mix delivers antimicrobial, anti‑inflammatory and antifungal effects at the site of application.

Side Effects

Mekostest 36 may cause local skin reactions and, rarely, systemic effects.

Common Side Effects

  • Skin irritation or burning sensation.
  • Pruritus or mild itching.
  • Erythema or redness at the application site.
  • Dryness or peeling of the skin.
  • Contact dermatitis.
  • Mild stinging.

Serious or Rare Side Effects

  • Allergic reaction with swelling, hives or angioedema.
  • Secondary infection due to over‑growth of resistant organisms.
  • Systemic corticosteroid effects such as adrenal suppression when used over large areas.
  • Severe skin necrosis or ulceration.
  • Anaphylaxis (rare).

Precautions & Warnings

When using Mekostest 36, follow these safety measures.

  • Avoid application on extensive broken skin: limit use to small affected areas.
  • Do not use on the face or mucous membranes unless directed by a clinician.
  • Limit duration of therapy: typically no longer than 2 weeks without medical review.
  • Monitor for signs of infection or allergic reaction and discontinue if they occur.
  • Contraindicated in patients with known hypersensitivity to any component.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Mekostest 36 can interact with other medications applied to the skin or taken systemically.

Major Interactions (Avoid)

  • Concurrent use of systemic corticosteroids: may increase risk of systemic steroid effects.
  • Other topical antibiotics: can promote resistant bacterial strains.
  • Immunosuppressive agents: heightened risk of opportunistic skin infections.

Moderate Interactions (Monitor Closely)

  • Occlusive dressings: may enhance percutaneous absorption of corticosteroids.
  • Topical antifungal agents: assess for additive irritation.
  • Wound‑healing products containing zinc or copper: may interfere with clioquinol activity.

Frequently Asked Questions

Mekostest 36 is a topical combination indicated for bacterial skin infections such as impetigo, inflammatory dermatoses like atopic or contact dermatitis, and mild superficial fungal infections. It may also be employed for seborrheic dermatitis and minor burn care when a broad‑spectrum antimicrobial and anti‑inflammatory effect is desired.

Bacitracin inhibits bacterial cell‑wall synthesis by interfering with the dephosphorylation of bactoprenol, a carrier molecule essential for peptidoglycan assembly. This action stops bacterial growth, allowing the immune system to clear the infection. In the combination product, bacitracin works alongside corticosteroids and antiseptics to provide a multi‑modal therapeutic effect.

The dosage of Mekostest 36 is determined by the prescribing healthcare professional based on the specific indication, severity, patient age and the size of the affected area. Typically, a thin layer is applied to the cleaned skin once or twice daily, but exact instructions should always follow the prescriber's order.

Safety data for Mekostest 36 in pregnancy and lactation are limited. Because the product contains corticosteroids and multiple antimicrobial agents, it should be used only if the potential benefit outweighs any possible risk. Pregnant or nursing women should discuss use with their physician before applying the medication.

To request Mekostest 36, visit the product page on gnhindia.com, enter the required quantity and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Mekostest 36 offers a broader spectrum than single‑agent topical antibiotics because it combines bacitracin with additional corticosteroids, antiseptics and an antifungal component. This multi‑ingredient approach can address mixed bacterial‑fungal infections and inflammatory skin conditions in one formulation, whereas many alternatives target only one type of pathogen or inflammation.

Store Mekostest 36 at room temperature, preferably below 25 °C. Keep the tube or container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use. Do not freeze the product, and discard any portion that appears discoloured or contaminated.

Mekostest 36 is applied topically to the affected skin area. Clean and gently dry the area, then spread a thin, even layer of the cream or ointment as directed by the prescriber, usually once or twice daily. Wash hands before and after application unless the hands are the treatment site.

Serious risks include allergic reactions such as hives, swelling or anaphylaxis, secondary infections due to resistant organisms, and systemic corticosteroid effects like adrenal suppression when used over large body surfaces or for prolonged periods. Patients should seek immediate medical attention if they experience severe skin reactions or systemic symptoms.

Mekostest 36 should be avoided in individuals with known hypersensitivity to any of its components, including bacitracin, corticosteroids, bronopol, chlorquinaldol or clioquinol. It is also contraindicated on extensive broken skin, on the face or mucous membranes unless specifically prescribed, and in patients receiving systemic immunosuppressive therapy without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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