Product image of Melabon K (Paracetamol, Acetylsalicylic Acid, Caffeine) supplied by GNH India

Melabon K

Active Ingredient:
Paracetamol, Acetylsalicylic Acid, Caffeine
Origin:
EU

Melabon K (Paracetamol, Acetylsalicylic Acid, Caffeine)

Paracetamol, Acetylsalicylic Acid and Caffeine, the active ingredients in Melabon K, are analgesic agents presented as a combination oral tablet for oral use. It treats headache, migraine, musculoskeletal pain and fever in adults.

GNH India supplies Melabon K as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medice Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Melabon K, a fixed‑dose combination analgesic, is indicated for conditions where pain and fever are present.

  • Headache: provides rapid relief of pain and associated discomfort.
  • Migraine: reduces headache intensity and improves functional ability.
  • Musculoskeletal pain: alleviates pain from strains, sprains and arthritic conditions.
  • Fever: lowers elevated body temperature.

How It Works

  • Paracetamol acts centrally to inhibit cyclo‑oxygenase enzymes, reducing pain and fever. Acetylsalicylic acid irreversibly blocks COX‑1 and COX‑2, delivering anti‑inflammatory, analgesic and antipyretic effects. Caffeine antagonises adenosine receptors, enhancing the analgesic activity of the other two components and contributing to increased alertness.

Side Effects

Common Side Effects

  • Nausea
  • Stomach upset or heartburn
  • Insomnia or difficulty sleeping
  • Dizziness

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions such as rash, swelling or anaphylaxis
  • Liver function abnormalities, including elevated transaminases.

Precautions & Warnings

Before using Melabon K, consider the following precautions.

  • Assess liver function: check baseline enzymes if prolonged use is anticipated.
  • Avoid in known aspirin allergy: contraindicated due to acetylsalicylic acid.
  • Use with caution in asthma: monitor for bronchospasm.
  • Limit alcohol intake: concurrent use increases risk of liver injury.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Melabon K may interact with several medicines; review the following.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin-containing products: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • CYP1A2 inhibitors (e.g., fluvoxamine): may raise caffeine levels.
  • Diuretics: aspirin can reduce renal clearance, requiring monitoring.
  • Methotrexate: aspirin may increase methotrexate toxicity.

Frequently Asked Questions

Melabon K is an over‑the‑counter combination of paracetamol, acetylsalicylic acid and caffeine used to relieve mild to moderate pain such as headache, migraine, musculoskeletal discomfort, and to reduce fever.

Paracetamol reduces pain and fever by centrally inhibiting COX enzymes. Acetylsalicylic acid irreversibly blocks COX‑1 and COX‑2, providing anti‑inflammatory, analgesic and antipyretic effects. Caffeine blocks adenosine receptors, which enhances the analgesic impact of the other two ingredients and can improve alertness.

The appropriate dose of Melabon K is determined by the prescribing healthcare professional based on the individual’s age, condition and response. Patients should follow the prescriber’s instructions and the product labeling.

Safety of Melabon K in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning pregnancy, or nursing should discuss potential risks and benefits with their healthcare provider before using this product.

To order Melabon K, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Melabon K combines three agents—paracetamol, aspirin and caffeine—offering a broader spectrum of pain relief and fever reduction than single‑ingredient products. Compared with paracetamol alone, the addition of aspirin adds anti‑inflammatory activity, while caffeine can improve analgesic efficacy and counteract drowsiness.

Melabon K should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture and direct sunlight to maintain product stability.

Melabon K is taken orally with a glass of water. It can be taken with or without food, but if stomach upset occurs, it may be helpful to take it with a light meal.

Serious risks include gastrointestinal bleeding, severe allergic reactions such as rash or anaphylaxis, and liver function abnormalities. Patients experiencing any of these should seek immediate medical attention.

Melabon K should be avoided by individuals with known hypersensitivity to paracetamol, aspirin or caffeine, those with active peptic ulcer disease, uncontrolled asthma triggered by aspirin, severe liver disease, or who are taking anticoagulant therapy without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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