Product image of Meladura (Melatonin) supplied by GNH India

Meladura

Active Ingredient:
Melatonin
Origin:
EU

Meladura (Melatonin)

Melatonin, the active ingredient in Meladura, is a melatonin receptor agonist presented as an oral formulation for oral use. It helps regulate sleep patterns and is used to manage insomnia, sleep‑wake cycle disorders and jet lag in adults. The product complies with EU quality standards.

GNH India supplies Meladura as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Melatonin acts on the melatonin receptor pathway to regulate circadian rhythm and is used for several sleep‑related conditions.
  • Insomnia: improves sleep onset and maintenance in individuals with difficulty falling or staying asleep.
  • Sleep‑wake cycle disorders: helps synchronize abnormal sleep patterns such as delayed sleep phase syndrome.
  • Jet lag: reduces the time needed to adjust to new time zones after long‑distance travel.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking the endogenous hormone. Activation of these G‑protein‑coupled receptors modulates intracellular signaling pathways that shift the circadian clock, promoting sleep initiation and stabilizing the sleep‑wake cycle.

Side Effects

Melatonin may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Drowsiness or daytime sleepiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams or nightmares
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching, or swelling
  • Mood changes including depression or anxiety
  • Hormonal effects like menstrual irregularities
  • Severe hypotension (very low blood pressure)

Precautions & Warnings

  • When considering melatonin therapy, several safety measures should be observed.
  • Pregnancy: consult a healthcare professional before use, as safety data are limited.
  • Breastfeeding: discuss potential risks with a physician.
  • Pediatric use: only under medical supervision, especially for chronic conditions.
  • Drug interactions: review concomitant medications for possible interactions.
  • Underlying conditions: assess for depression, seizure disorders, or autoimmune diseases before initiating therapy.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Melatonin can interact with other medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): possible reduction in drug efficacy.
  • Central nervous system depressants (e.g., benzodiazepines): excessive sedation.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: potential alteration of hormone levels.
  • Antidiabetic agents: possible effect on blood glucose control.
  • Antihypertensives: may enhance blood pressure‑lowering effect.

Frequently Asked Questions

Meladura contains melatonin, which is used to help regulate the sleep‑wake cycle. It is indicated for occasional insomnia, circadian rhythm sleep‑wake disorders and for reducing the effects of jet lag after rapid travel across time zones.

Melatonin acts as an agonist at MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. By binding these receptors, it signals darkness to the body, helping to shift and synchronize the internal clock, which promotes sleep onset and stabilises sleep patterns.

The appropriate dose of Meladura is determined by the prescribing clinician based on the individual’s age, condition, and response. Dosage may vary, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for melatonin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Meladura.

To request Meladura, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Meladura (melatonin) differs from traditional hypnotics such as benzodiazepines or Z‑drugs because it works by mimicking the body’s natural hormone rather than depressing central nervous system activity. It is generally considered for short‑term or circadian‑related sleep issues, whereas other classes may be used for chronic insomnia but carry higher risks of dependence.

Meladura should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Meladura is taken orally, usually with a glass of water. The tablet (or other oral form) is swallowed whole and should be taken according to the timing recommended by the prescriber, often 30‑60 minutes before the desired bedtime.

Serious but rare risks include allergic reactions such as rash, itching, swelling, or difficulty breathing, and significant mood changes like depression or anxiety. Any signs of severe reaction should prompt immediate medical attention.

Individuals with known hypersensitivity to melatonin, those taking medications that have major interactions (e.g., anticoagulants, immunosuppressants, CNS depressants) without medical supervision, and patients with uncontrolled endocrine or psychiatric disorders should avoid using Meladura unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.