Product image of Melatonin Alturix (Melatonin) supplied by GNH India

Melatonin Alturix

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Alturix (Melatonin)

Melatonin, the active ingredient in Melatonin Alturix, is a melatonin receptor agonist presented as an oral formulation for oral use. It is used to help regulate the circadian rhythm and promote sleep onset in adults experiencing insomnia, jet lag, or other sleep‑wake rhythm disturbances.

GNH India supplies Melatonin Alturix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Manufactured under EU GMP guidelines, the product meets European pharmacopoeial specifications for purity and potency. It is distributed through GNH India's regulated supply chain to ensure consistent quality across markets.

Manufacturer / TM Owner

Alturix Limited

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Indications & Clinical Uses

Melatonin Alturix is a melatonin receptor agonist indicated for several sleep‑related conditions.

  • Insomnia: facilitates sleep onset and improves sleep continuity in individuals with difficulty falling or staying asleep.
  • Jet lag: helps realign the internal clock after rapid east‑west travel, reducing sleep disturbances and daytime fatigue.
  • Sleep‑wake rhythm disorders: supports normalization of abnormal circadian patterns in shift‑work or delayed‑sleep‑phase syndrome.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus of the hypothalamus, mimicking the endogenous hormone that signals darkness. Activation of these G‑protein‑coupled receptors reduces neuronal firing, leading to a decrease in core body temperature and promotion of sleep propensity. By reinforcing the physiological night‑time signal, melatonin helps synchronize the circadian rhythm and facilitates the transition to sleep.

Side Effects

Melatonin Alturix may cause a range of adverse reactions, which are generally mild but can be serious in rare cases.

Common Side Effects

  • Headache: mild to moderate pain often occurring shortly after ingestion.
  • Dizziness: transient light‑headedness that usually resolves without intervention.
  • Daytime sleepiness: feeling unusually drowsy during waking hours.
  • Nausea: mild stomach upset or queasiness.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing indicating possible anaphylaxis.
  • Severe mood changes: depression or vivid hallucinations requiring immediate medical attention.
  • Cardiac arrhythmia: irregular heartbeat reported in isolated cases.

Precautions & Warnings

When considering Melatonin Alturix, several precautionary measures should be observed to ensure safe use.

  • Assess underlying sleep disorder: confirm diagnosis before initiating therapy.
  • Avoid concomitant alcohol: alcohol may enhance sedative effects.
  • Caution in hepatic impairment: reduced metabolism may increase exposure.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Review concomitant medications: evaluate potential drug interactions.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Melatonin Alturix can interact with other medicines; understanding the level of interaction helps guide clinical decisions.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): melatonin may increase bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): altered melatonin metabolism may affect drug levels.
  • Central nervous system depressants (e.g., benzodiazepines): additive sedative effect.

Moderate Interactions (Monitor Closely)

  • CYP1A2 inhibitors (e.g., fluvoxamine): can raise melatonin concentrations.
  • CYP1A2 inducers (e.g., rifampin): may reduce melatonin effectiveness.

Frequently Asked Questions

Melatonin Alturix is used to support the regulation of the sleep‑wake cycle. It is prescribed for adults who have difficulty falling asleep (insomnia), experience disrupted sleep after rapid travel across time zones (jet lag), or have circadian rhythm disorders such as shift‑work sleep disorder. By acting on melatonin receptors, it helps promote the onset of sleep and improve overall sleep quality.

Melatonin is a hormone that signals darkness to the brain. When taken as a supplement, it binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, the body’s internal clock. This binding reduces neuronal activity, lowers core body temperature, and creates a physiological environment that encourages sleep, thereby helping to synchronize the circadian rhythm with the external light‑dark cycle.

The appropriate dose of Melatonin Alturix is determined by a qualified healthcare professional based on the individual’s age, condition, and response to therapy. The prescriber will select the strength and timing that best fits the patient’s specific sleep disorder, and patients should follow the prescribed instructions without altering the dose on their own.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting Melatonin Alturix. The prescriber will weigh the need for sleep support against any possible effects on the fetus or infant.

To request Melatonin Alturix, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Melatonin Alturix differs from traditional hypnotics such as benzodiazepines or Z‑drugs because it works by mimicking a natural hormone rather than depressing the central nervous system. This mechanism typically results in fewer next‑day residual effects and a lower risk of dependence. However, its efficacy may be more modest for severe insomnia, and it is best suited for circadian‑related sleep disturbances.

Melatonin Alturix should be stored at ambient temperature, below 25 °C, in its original packaging. The container should be kept tightly closed, protected from moisture, heat and direct sunlight. Proper storage helps maintain the product’s potency and prevents degradation over time.

Melatonin Alturix is taken orally, usually as a tablet or capsule, and is typically administered 30‑60 minutes before the desired bedtime. The exact timing and formulation should follow the prescribing clinician’s instructions to align with the patient’s sleep schedule and maximize effectiveness.

Although uncommon, serious adverse reactions can include severe allergic responses such as rash, swelling, or breathing difficulties, as well as significant mood changes like depression or vivid hallucinations. Any signs of anaphylaxis or sudden psychiatric symptoms should prompt immediate medical attention.

Melatonin Alturix is not recommended for individuals with known hypersensitivity to melatonin or any excipients in the formulation. Patients with uncontrolled severe hepatic impairment, those taking medications that may cause dangerous interactions (e.g., certain anticoagulants or CNS depressants), and individuals for whom sleep is not the primary issue should avoid use unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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