Product image of Melatonin Bluefish (Melatonin) supplied by GNH India

Melatonin Bluefish

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Bluefish (Melatonin)

Melatonin, the active ingredient in Melatonin Bluefish, is a melatonin receptor agonist presented as an oral supplement for oral use. It is employed to support normal sleep patterns in adults experiencing insomnia or circadian‑rhythm disturbances.
GNH India supplies Melatonin Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Melatonin acts on melatonin receptors to regulate the circadian rhythm and is used for sleep‑related disorders.

  • Insomnia: helps reduce sleep onset latency and improve total sleep time.
  • Sleep‑wake rhythm disorders: assists in aligning the internal clock with desired sleep‑wake schedules.
  • Delayed sleep phase syndrome: promotes earlier sleep onset and more consistent sleep timing.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking the endogenous hormone that signals darkness. This agonist activity modulates the circadian pacemaker, facilitating the transition to sleep and stabilising the sleep‑wake cycle without directly depressing central nervous system activity.

Side Effects

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Drowsiness: may persist into the next morning.
  • Dizziness: transient episodes.
  • Nausea: occasional gastrointestinal upset.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Mood changes: depression or increased anxiety in susceptible individuals.
  • Hormonal effects: rare alterations in menstrual cycle or reproductive hormones.

Precautions & Warnings

Melatonin should be used with awareness of specific safety considerations.

  • Pregnancy: consult a healthcare professional before use, as safety data are limited.
  • Breastfeeding: discuss potential risks with a clinician.
  • Concomitant CNS depressants: monitor for additive drowsiness.
  • Anticoagulants: observe for any changes in bleeding tendency.
  • Underlying psychiatric conditions: use caution if prone to mood disorders.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Melatonin may interact with several drug classes, requiring attention to potential effects.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): possible reduction in efficacy.

Moderate Interactions (Monitor Closely):\n- CNS depressants (e.g., benzodiazepines, antihistamines): enhanced sedation.

  • Oral contraceptives: potential reduction in contraceptive effectiveness.
  • CYP1A2 inhibitors (e.g., fluvoxamine): elevated melatonin plasma levels.
  • Antidiabetic agents: monitor blood glucose for possible alterations.

Frequently Asked Questions

Melatonin Bluefish contains melatonin, a hormone that helps regulate the sleep‑wake cycle. It is used primarily to manage insomnia and other sleep‑wake rhythm disorders by supporting the body’s natural circadian timing.

Melatonin binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, mimicking the natural hormone released at night. This signaling tells the body that it is dark, promoting sleep onset and helping to synchronize internal biological rhythms.

The appropriate dose of Melatonin Bluefish is determined by the prescribing clinician based on the individual’s age, condition, and response. Dosage may vary, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for melatonin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike many sedative hypnotics, melatonin works by aligning the body’s circadian clock rather than depressing central nervous system activity. This mechanism often results in fewer next‑day residual effects, but effectiveness can vary depending on the underlying sleep disorder and individual response.

Melatonin Bluefish should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The product is taken orally, typically as a tablet or capsule, with water. It is usually taken shortly before bedtime, following the dosage instructions provided by the prescriber to align with the individual’s sleep schedule.

Serious but rare risks include allergic reactions such as rash, itching, swelling, or difficulty breathing, and mood alterations like increased anxiety or depression. Patients experiencing any of these symptoms should seek medical attention promptly.

Individuals with known hypersensitivity to melatonin, those taking medications that have major interactions (e.g., anticoagulants, immunosuppressants), and patients with uncontrolled psychiatric conditions should avoid using the product unless advised otherwise by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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