Product image of Melatonin Glenmark (Melatonin) supplied by GNH India

Melatonin Glenmark

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Glenmark (Melatonin)

Melatonin, the active ingredient in Melatonin Glenmark, is a melatonin receptor agonist presented as an oral formulation for oral use. It helps regulate the circadian rhythm and is used to support sleep onset in adults experiencing insomnia, jet lag, or other sleep‑onset difficulties. The product is manufactured under EU GMP guidelines and is intended for short‑term use under medical supervision.

GNH India supplies Melatonin Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Melatonin Glenmark acts on melatonin receptors to address disorders of sleep regulation.

  • Insomnia: improves sleep onset and duration in individuals with difficulty falling asleep.
  • Sleep onset difficulties: facilitates quicker transition to sleep in patients with delayed sleep phase.
  • Jet lag: helps realign circadian rhythm after rapid time‑zone travel, reducing fatigue.

How It Works

  • Melatonin Glenmark contains melatonin, which binds to MT1 and MT2 receptors in the suprachiasmatic nucleus of the brain. Activation of these G‑protein‑coupled receptors modulates the internal clock, promoting the physiological signals that initiate sleep. By mimicking the endogenous hormone, the drug enhances the night‑time signal cascade, thereby supporting the natural circadian rhythm and facilitating sleep onset.

Side Effects

Oral melatonin may be associated with a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Drowsiness: feeling unusually sleepy during the day.
  • Headache: mild to moderate head pain.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Nausea: upset stomach or urge to vomit.

Serious or Rare Side Effects

  • Allergic reactions: rash, swelling, or hives indicating hypersensitivity.
  • Mood changes: emergence of depression, anxiety, or irritability.

Precautions & Warnings

Before using Melatonin Glenmark, consider the following precautions.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown; weigh potential risks against benefits.
  • Concomitant CNS depressants: may increase sedation.
  • Elderly: start with the lowest dose due to increased sensitivity.
  • Medical conditions: caution in patients with autoimmune disorders.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Melatonin Glenmark can interact with other medicines; monitor as indicated.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may increase bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): may reduce melatonin clearance.

Moderate Interactions (Monitor Closely)

  • CNS depressants (benzodiazepines, antihistamines): additive drowsiness.
  • Oral contraceptives: may alter melatonin metabolism.
  • Antidepressants (SSRIs): potential serotonin‑related effects.

Frequently Asked Questions

Melatonin Glenmark is used to support the natural sleep‑wake cycle in adults who have difficulty falling asleep, experience insomnia, or suffer from jet lag after rapid travel across time zones. By acting on melatonin receptors, it helps promote sleep onset and improve overall sleep quality when used under medical guidance.

Melatonin works by binding to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, the central regulator of circadian rhythms. This activation signals the body that it is nighttime, helping to synchronize internal clocks, reduce alertness, and facilitate the physiological processes that lead to sleep.

The appropriate dose of Melatonin Glenmark is determined by a qualified prescriber based on the individual’s age, health status, and specific sleep concern. Dosage may vary, and patients should follow the prescribing clinician’s instructions without self‑adjusting the amount.

Safety data for melatonin use in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a healthcare professional after a thorough evaluation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Melatonin Glenmark differs from prescription hypnotics such as zolpidem or benzodiazepines because it mimics a naturally occurring hormone rather than acting on GABA receptors. It generally has a milder side‑effect profile and is not classified as a controlled substance, making it suitable for short‑term use in circadian‑related sleep disturbances.

Store Melatonin Glenmark at ambient temperature, preferably below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Melatonin Glenmark is taken orally, typically as a tablet or capsule, with water. It is usually taken 30‑60 minutes before the desired bedtime to align with the body’s natural night‑time signaling. Patients should follow the timing instructions provided by their prescriber.

Serious risks, though rare, include allergic reactions such as rash, swelling, or hives, and significant mood changes like depression or heightened anxiety. If any of these symptoms occur, the user should discontinue the product and seek immediate medical attention.

Melatonin Glenmark should be avoided by individuals with known hypersensitivity to melatonin, those taking certain anticoagulants or immunosuppressants without medical supervision, and patients with severe hepatic impairment. Children, pregnant or nursing women should only use it if a healthcare professional explicitly recommends it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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