Melatonin

Melatonin acts as an agonist at MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, helping to synchronize the internal clock with the external light‑dark cycle, which promotes the onset of sleep and stabilizes the sleep‑wake rhythm.

The appropriate dose of melatonin is determined by a prescriber based on the specific indication, patient age, and clinical response. Dosage may vary widely, so it should always follow the healthcare professional’s recommendation.

Safety data for melatonin use in pregnancy or while breastfeeding are limited. Healthcare providers usually advise caution and may recommend avoiding melatonin unless the potential benefit outweighs any possible risk.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Unlike sedative hypnotics that act on GABA receptors, melatonin works by mimicking the body’s natural hormone to regulate circadian rhythms. It is generally considered non‑habit forming and may be preferred for short‑term adjustment of sleep timing, though efficacy varies by individual and condition.

Store melatonin at room temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct light, and ensure the seal remains intact to maintain potency.

Melatonin is taken orally, typically as a tablet, capsule, or liquid formulation. It is usually taken shortly before bedtime, following the prescribing healthcare professional’s instructions regarding timing and any food considerations.

Serious risks, though rare, include severe allergic reactions such as rash, swelling, or difficulty breathing, as well as significant mood changes like depression or anxiety, and abnormal heart rhythms. Any of these symptoms should prompt immediate medical evaluation.

Individuals with known hypersensitivity to melatonin, those taking certain interacting medications (e.g., anticoagulants, immunosuppressants, CNS depressants), and patients with uncontrolled hepatic disease should avoid melatonin unless advised otherwise by a healthcare professional.