Melatonin

Melatonin works by binding to MT1 and MT2 receptors in the brain, especially in the suprachiasmatic nucleus. This interaction reduces neuronal activity that promotes wakefulness and helps shift the timing of the circadian rhythm, thereby supporting the onset of sleep.

The appropriate dose of melatonin is determined by a prescriber based on the individual’s age, condition, and response to therapy. Patients should follow the dosage instructions provided by their healthcare professional and not self‑adjust the amount.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before starting melatonin.

To order melatonin, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Melatonin differs from antihistamine or benzodiazepine sleep aids because it works by mimicking a natural hormone rather than depressing the central nervous system. It generally has a favorable safety profile and is less likely to cause dependence, but its efficacy may be modest compared with prescription hypnotics for severe insomnia.

Melatonin should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and direct light. Keeping the product in a dry, cool place helps maintain its potency throughout its shelf life.

Melatonin is taken orally, usually as a tablet, capsule or liquid. It can be taken with or without food, typically 30‑60 minutes before bedtime, as directed by a healthcare professional.

Serious risks, although rare, include severe allergic reactions such as anaphylaxis, significant mood changes like depression or irritability, and pronounced hormonal effects that may alter menstrual cycles. Any signs of these reactions should prompt immediate medical attention.

Melatonin should be avoided by individuals with known hypersensitivity to the product, children without medical supervision, and patients taking certain medications such as anticoagulants or immunosuppressants unless advised by a physician. Those with uncontrolled epilepsy or severe psychiatric disorders should also consult a healthcare provider before use.