Melatonin

Melatonin works by binding to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. This mimics the body’s natural hormone, signalling that it is night‑time, which helps to initiate sleep and align the internal circadian clock with the external environment.

The appropriate dose of melatonin is determined by a prescriber based on the individual’s age, condition, and response to therapy. Dosage may vary widely, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for melatonin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using melatonin.

To order melatonin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Unlike many prescription hypnotics that act on GABA receptors, melatonin works by mimicking the natural hormone that regulates circadian rhythms. It is generally considered to have a milder side‑effect profile and is often preferred for short‑term use or for adjusting sleep patterns related to travel or shift work.

Melatonin should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency.

Melatonin is taken orally, typically as a tablet or capsule, with water. It is usually taken shortly before bedtime, but the exact timing and frequency should follow the prescribing clinician’s instructions.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, significant mood changes like depression or suicidal thoughts, and rare seizure activity. Patients should seek immediate medical attention if they experience any of these symptoms.

Melatonin should be avoided by individuals with known hypersensitivity to the product, those taking certain medications that have major interactions (e.g., warfarin, cyclosporine, fluoxetine, carbamazepine), and by children unless specifically prescribed by a qualified healthcare professional.