Product image of Melatonin Neuraxpharm (Melatonin) supplied by GNH India

Melatonin Neuraxpharm

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Neuraxpharm (Melatonin)

Melatonin, the active ingredient in Melatonin Neuraxpharm, is a melatonin receptor agonist presented as an oral formulation for oral use. It is used to support normal sleep patterns in adults experiencing sleep disturbances. GNH India supplies Melatonin Neuraxpharm as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Neuraxpharm Arzneimittel Gmbh

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Indications & Clinical Uses

Melatonin Neuraxpharm acts on the melatonin MT1 and MT2 receptors to help regulate the sleep‑wake cycle.

  • Insomnia: assists individuals in falling asleep more quickly and improving sleep continuity.
  • Jet lag: aids adjustment of the circadian rhythm after rapid travel across time zones.
  • Shift work disorder: promotes sleep during daytime hours for workers on non‑traditional schedules.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking the endogenous hormone that signals darkness. This activation modulates circadian rhythm genes and reduces neuronal activity that promotes wakefulness, thereby facilitating the onset of sleep and supporting a regular sleep‑wake pattern.

Side Effects

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or daytime sleepiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams or nightmares

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching, or swelling
  • Mood changes including depression or anxiety
  • Hormonal effects like menstrual irregularities
  • Severe hypotension (very low blood pressure)

Precautions & Warnings

Melatonin should be used with awareness of certain safety considerations.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Concomitant anticoagulant therapy: monitor for increased bleeding tendency.
  • Driving or operating machinery: may cause drowsiness; caution is advised.
  • Known hypersensitivity: avoid if allergic to melatonin or excipients.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Melatonin may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • CYP1A2 inhibitors (e.g., fluvoxamine): can raise melatonin plasma levels.
  • Anticoagulants (e.g., warfarin): may enhance bleeding risk.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): additive sedative effect.
  • Oral contraceptives: may increase melatonin concentrations.
  • Antidepressants (SSRIs): possible alteration of sleep architecture.

Frequently Asked Questions

Melatonin Neuraxpharm is used to support the regulation of the sleep‑wake cycle in adults who have difficulty falling asleep or maintaining sleep, such as those with insomnia, jet lag, or shift‑work related sleep disturbances.

Melatonin acts as an agonist at the MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, signaling darkness and helping to synchronize the circadian rhythm, which promotes the onset of sleep.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s condition, age, and response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data are limited; therefore, pregnant or breastfeeding individuals should discuss potential risks and benefits with their healthcare provider before using melatonin.

Enquiries can be submitted via the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Unlike many prescription hypnotics that act on GABA receptors, melatonin works by mimicking the body’s natural hormone to reset circadian rhythms. It is generally considered to have a milder side‑effect profile, but effectiveness may vary depending on the underlying sleep disorder.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain stability.

Melatonin Neuraxpharm is taken orally, usually with a glass of water. It is commonly taken 30–60 minutes before the desired bedtime, but the exact timing should follow the prescriber’s guidance.

Serious risks, though rare, include severe allergic reactions such as rash, swelling, or difficulty breathing, and significant hormonal effects like menstrual irregularities. Any unexpected symptoms should prompt immediate medical attention.

Individuals with known hypersensitivity to melatonin or any excipients, those taking certain interacting medications without medical supervision, and patients with uncontrolled endocrine disorders should avoid using the product unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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